Representative histological images of aorta from WT, ApoEm/m and ApoE−/− pigs. Representative histological images of aorta from WT, ApoEm/m and ApoE−/− pigs. No visible atherosclerosis was seen in the aorta from WT pigs (A,D,G). ApoEm/m pigs had pathological fatty streak of the aorta (B,E,H). ApoE−/− pigs showed progressive atherosclerotic lesions in the luminal part of the arterial intima (C,F,I). Bin Fang et al. Dis. Model. Mech. 2018;11:dmm036632 © 2018. Published by The Company of Biologists Ltd