Bradykinin preconditioning in coronary artery bypass grafting

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Bradykinin preconditioning in coronary artery bypass grafting Minxin Wei, MD, PhD, Xin Wang, MD, Pekka Kuukasjärvi, MD, PhD, Jari Laurikka, MD, PhD, Timo Rinne, MD, PhD, Eva-Liisa Honkonen, MD, PhD, Matti Tarkka, MD, PhD The Annals of Thoracic Surgery Volume 78, Issue 2, Pages 492-497 (August 2004) DOI: 10.1016/j.athoracsur.2003.11.039

Fig 1 Heart rate and MBP change during bradykinin infusion. Significant decrease of MBP and HR were seen during the infusion. *p < 0.05 as compared to the baseline blood pressure; • = HR; ○ = MBP. (HR = heart rate; MPB = mean blood pressure.) The Annals of Thoracic Surgery 2004 78, 492-497DOI: (10.1016/j.athoracsur.2003.11.039)

Fig 2 Perioperative levels of CKMB in bradykinin patients and controls. The BK group release significantly lowers CKMB as compared to the controls (analysis of variance for repeated measurements, p = 0.036). • = BK; ○ = control. (BK = bradykinin group; CKMB = creatine kinase cardiac isoenzyme.) The Annals of Thoracic Surgery 2004 78, 492-497DOI: (10.1016/j.athoracsur.2003.11.039)