High-resolution imaging of multi-focal dispersion of acute B

Slides:

Advertisements

Similar presentations

Mitochondria localize to both the front and the rear of neutrophils.

Advertisements

Immuno-gold localisation of COPI in N. gruberi cells.

Il1b is required for the early and late recruitment of neutrophils but not macrophages. Il1b is required for the early and late recruitment of neutrophils.

Representative histopathology images from the knee joints and ankle of CAIA mice injected s.c. with GalNAc–MASP-3–siRNA duplex 2 or GalNAc–luciferase–siRNA.

Fig. 7 Gel scaffold for inhibition of postsurgical recurrence of B16F10 tumors. Gel scaffold for inhibition of postsurgical recurrence of B16F10 tumors.

Effect of cxcr3.2 mutation on dissemination of local mycobacterial infection within 24 hpi. Effect of cxcr3.2 mutation on dissemination of local mycobacterial.

mTOR downregulation, but not autophagy, reduces VAP(P58S) aggregation.

Retinoic acid sentinels in live embryos and responding to exogenous RA in half-embryo cultures. Retinoic acid sentinels in live embryos and responding.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown AZ-521 cells. VacA does not induce phosphorylation of Src in RPTPα constitutive-knockdown.

Azithromycin treatment eliminates NTHi infection.

Representative histological images of aorta from WT, ApoEm/m and ApoE−/− pigs. Representative histological images of aorta from WT, ApoEm/m and ApoE−/−

A Drosophila cell culture model to study VAP(P58S) aggregation.

OA and related amines modulate motility and length of schistosomula.

C. elegans cell-lineage map and multi-vulva mutants.

Fig. 10. Ratiometric live imaging of di-4-ANEPPDHQ in growing pollen tubes.(A) Higher and lower membrane order distribution in control and BCD treated.

Tbx1 regulates the Mef2c AHF enhancer in vivo.

X-ray radiographic images showing structural alterations of the joints that are most commonly affected by OA. (A) Normal and (A′) severely affected joint.

OCT and IOP analysis of 2-3-month-old AP-2β NCC KO mutants.

Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.

Crotonate increases histone crotonylation in mouse kidney.

Effect of OLHHA on the protein expression of relevant enzymes and factors related to lipid metabolism in the liver of obese Zucker rats. Effect of OLHHA.

TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.

Scanning EM shows cilia abnormalities in the neural tube.

Challenge with oxazolone results in epithelial hyperplasia and influx of inflammatory cells into the epidermis and dermis and keratosis as observed in.

Hypoacidity, anemia and hypergastrinemia in KI/KI mice.

Fig. 1. E-cadherin localizes in nano-scale clusters.

Fig. 1. Pigmentation and melanophore counts of rainbow trout parr and smolt caudal fins.Pigmentation of (A) parr and (B) smolt. Pigmentation and melanophore.

Fig. 3. Genetic interactions between unc-53 and unc-6 and between unc-53 and unc-5 affect intracellular UNC-40::GFP localization.(A–H) Photomicrographs.

Effect of 20E on locomotion behavior.

Brucella melitensis infectious foci in liver.

Obesity affected the metabolic response to stroke.

Effects of tumour size on response to treatment in the KPC model.

Expression data confirm and extend existing knowledge

The cellular and molecular differences between acute healing wounds and chronic non-healing wounds. The cellular and molecular differences between acute.

Acute hypoxia (12-hour windows).

Tamoxifen injections induce DNA damage response signaling in αMHC-MerCreMer mice.αMHC-MerCreMer+/+ mice received an injection of 60 μg/g body weight of.

Elevated expression of vegfaa in hemangiosarcoma.

Inflammation,M. leprae infiltration and demyelination in infected armadillo PT nerve. Inflammation,M. leprae infiltration and demyelination in infected.

Distribution and extent of expression.

Comparison ofMyc-induced zebrafish liver tumors with different stages of human HCC and seven mouse HCC models. Comparison ofMyc-induced zebrafish liver.

Planarian brain regeneration.

Armadillos are the only natural host of leprosy, aside from humans.

The genomic distribution of essential and non-essential mouse genes, separated into known and predicted essentiality. The genomic distribution of essential.

Homozygous col22a1−/− embryos show increased percentage of hemorrhages when raised at increased temperature. Homozygous col22a1−/− embryos show increased.

Tissue ATP levels measured in the liver, muscle, kidney and pancreas of CDs/y and CDr/y on RD or DD. *P

EpiDEG efficiently degrades GFP-tagged proteins that localize to different subcellular localizations. epiDEG efficiently degrades GFP-tagged proteins that.

Nerve conduction slowing and DRG sensory neuron and nuclear atrophy in 16-week-old diabetic mice. Nerve conduction slowing and DRG sensory neuron and nuclear.

Anti-epileptic drugs with Na+ channel blocking activity improve QTc in individuals with Rett syndrome. Anti-epileptic drugs with Na+ channel blocking activity.

HEK-cFXN cells show a correlation among ROS levels, LIP and frataxin expression. HEK-cFXN cells show a correlation among ROS levels, LIP and frataxin expression.

Exo70 is recruited to the plasma membrane at sites of mechanical wounding. Exo70 is recruited to the plasma membrane at sites of mechanical wounding. NRK.

Spinal cord-like tissues were ventralized by activating Shh signaling in a dose-dependent manner. Spinal cord-like tissues were ventralized by activating.

Prophase nuclear movements in wild-type, rec8 and rec7 mutant cells.

Infection did not affect dendritic length of pyriform cortex, thus precluding a generalized retraction all over the brain. Infection did not affect dendritic.

Association of MMP expression with macrophages.

The zebrafish swdp75fm and swdp82mf mutations cause exocrine pancreatic hypoplasia and reduced skin pigmentation. The zebrafish swdp75fm and swdp82mf mutations.

Overexpression of cyp7a1 in the liver ameliorates tumor-induced liver inflammation. Overexpression of cyp7a1 in the liver ameliorates tumor-induced liver.

Peroxisome speeds were slower in patient and control cells.

Fig. 1. Generation of induced pluripotent stem cells (iPSCs) from urine cells (UC). Generation of induced pluripotent stem cells (iPSCs) from urine cells.

Time-lapse imaging of neutrophil migration in vivo.

Histology of Brucella bone marrow foci in mice.

Fig. 3. MO-mediated smc3 knockdown results in reduced regenerate length, segment length and cell proliferation. MO-mediated smc3 knockdown results in reduced.

Running on the treadmill prolonged TrkB activation induced by exogenous BDNF in vivo. Running on the treadmill prolonged TrkB activation induced by exogenous.

Histone crotonylation in kidney tubular cells.

Effects of paclitaxel and vinblastine.

Dynamic and polarized recruitment of ERC1a near protrusive sites during migration. Dynamic and polarized recruitment of ERC1a near protrusive sites during.

2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. 2DG suppresses of lamellipodia.

Subcellular distribution of Mst4 and aPKCι in in vivo enterocytes.

Upon challenge with oxazolone, human leukocytes (mainly consisting of T cells) infiltrate the dermis and epidermis. Upon challenge with oxazolone, human.

Cardiac MRI during the acute phase of the illness.

Presentation transcript:

High-resolution imaging of multi-focal dispersion of acute B High-resolution imaging of multi-focal dispersion of acute B. melitensis infection. High-resolution imaging of multi-focal dispersion of acute B. melitensis infection. With in vivo bioluminescent imaging at day 4 post-infection, Brucella was mainly localized intraperitoneally (IP), in the liver (L), knee (K), near ankle joint (A), metatarsophalangeal (MP), metatarsotarsal articulations (MT), calcaneus (C) and ventral processes of caudal vertebrae (Ca). Note the mirrored patterns of Brucella distribution in the left and right paws and knees. Color scale represents bioluminescent signals intensity. Arrows indicate formerly uncharacterized sites of bacterial infection in knees, paws and tail. Image taken at 1-minute integration time and four binning for higher-resolution setting. Diogo M. Magnani et al. Dis. Model. Mech. 2013;6:811-818 © 2013. Published by The Company of Biologists Ltd