Rhomboid-7, Pink1 and Omi physically interact in the mitochondria

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Rhomboid-7, Pink1 and Omi physically interact in the mitochondria Rhomboid-7, Pink1 and Omi physically interact in the mitochondria.(A) Co-expression of Rhomboid-7 and Omi (top row); Pink1 and Rhomboid-7 (middle row); and Pink1 and Omi (bottom row) in Drosophila S2 cells shows respective co-localization in mitochondria. Rhomboid-7, Pink1 and Omi physically interact in the mitochondria.(A) Co-expression of Rhomboid-7 and Omi (top row); Pink1 and Rhomboid-7 (middle row); and Pink1 and Omi (bottom row) in Drosophila S2 cells shows respective co-localization in mitochondria. (B) Immunoprecipitation of Rhomboid-7-FLAG with Omi-HA in S2 cells. (C) Immunoprecipitation of Rhomboid-7-FLAG with Pink1-HA in S2 cells. (D) Immunoprecipitation of Pink1-FLAG with Omi-HA in S2 cells. (E) Immunoprecipitation of Parkin-HA with Pink1-FLAG in S2 cells. Alexander J. Whitworth et al. Dis. Model. Mech. 2008;1:168-174 ©2008 by The Company of Biologists Limited