Haplotype map of S. cerevisiae RNQ1.

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Haplotype map of S. cerevisiae RNQ1. Haplotype map of S. cerevisiae RNQ1. Networks (A–K) representing haplotype connections, where nodes (black dots and shapes) represent a single mutation, were generated with TCS2.1. Each haplotype is represented with strain and haplotype identifiers (e.g., A or B), and colored according to the clade to which it was assigned; green, ancestral; orange, commercial beer; blue, commercial food; red, wine/vineyard. Haplotypes within each network are ordered top to bottom by increasing genetic divergence from S. paradoxus. Haplotype E (boxed area) was significantly associated with [PIN+] infection (Fisher’s exact: P < 0.001). Haplotypes were not connected to networks when the number of mutational events was greater than five. Amy C. Kelly et al. Genetics 2014;197:1007-1024 Copyright © 2014 by the Genetics Society of America