Figure 1. Heat map of antibody binding patterns to glycolipid targets in Guillain-Barré syndrome (GBS) cases and controls Heat map of antibody binding.

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Presentation transcript:

Figure 1. Heat map of antibody binding patterns to glycolipid targets in Guillain-Barré syndrome (GBS) cases and controls Heat map of antibody binding patterns to glycolipid targets in Guillain-Barré syndrome (GBS) cases and controls (A) Patient (GBS) and control sera (family controls [FC] and neurologic disease controls [NC]) were screened against a panel of 78 single and heteromeric glycolipid targets on glycolipid microarray. Mean fluorescent intensity values were calculated and graphically presented as a heat map. The rainbow scale indicates the intensity of the antibody binding, in which blue is weak and red is strong antibody binding. Pearson hierarchical clustering was employed to group samples with similar antigen binding patterns. (B) Heat map presentation of GBS samples for the 30 glycolipid targets identified as having significantly different binding intensities between GBS and FC or NC groups (p < 0.05). Susan K. Halstead et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e284 © 2016 American Academy of Neurology