Pulmonary cytokine expression in C57Bl/6 mice post IT-LPS.

Slides:

Advertisements

Similar presentations

Fig. 8. Changes of caspase-3 (A), Bcl-2 (B), IL-6 (C), TNF-α (D), VEGF (E) and BNP (F) protein expression levels after hUCB-MSCs injection in PAH rat heart.

Advertisements

by Odilo Engel, Levent Akyüz, Andrey C

Ex vivo effects of proNGF and NGF on JIA mononuclear cells.

The significantly different metabolites between the systemic inflammatory response syndrome SIRS (n=15) and sepsis (n=35) groups (A); the sepsis (n=10)

Effects of a caspase-1 inhibitor and NLRP3 inhibitor on nontypeable Haemophilus influenzae (NTHi)-induced interleukin (IL)-1β production. a) Peripheral.

Mary E. Huerter, MD, MA, Ashish K

Surgical removal of endometriotic lesions alters local and systemic proinflammatory cytokines in endometriosis patients Stephany P. Monsanto, M.Sc.,

S. S. Pullamsetti, R. Savai, W. Janssen, B. K. Dahal, W. Seeger, F

Oral and topical boswellic acid attenuates mouse osteoarthritis

Immunomodulatory activity of vardenafil on induced lung inflammation in cystic fibrosis mice Bob Lubamba, François Huaux, Jean Lebacq, Etienne Marbaix,

Cross sectional comparisons of GAPDH and β-actin gene expression.

Yiping Wang, Yuet-Ching Tay, David C.H. Harris Kidney International

Delivery of formyl peptide receptor 1 (FPR1) antagonist cyclosporin H reduces neutrophil recruitment in acid-induced lung inflammation. Delivery of formyl.

Formyl peptide receptor 1 (FPR1) is expressed on pulmonary epithelial cells with myeloid and parenchymal cell FPR1 contributing to neutrophil recruitment.

Α7 Nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury M. Kox, J.C. Pompe,

Patients with exacerbations of chronic obstructive pulmonary disease admitted to hospital according to the day of the week (A), and presenting to the emergency.

Monthly admissions for chronic obstructive pulmonary disease (COPD) to Christchurch Hospital. Monthly admissions for chronic obstructive pulmonary disease.

The top 25 analytes by relevant q-value differentially expressed in HIV with COPD. The top number is m/z and the bottom number is RT. Y-axis is intensity.

Change of proinflammatory cytokines follows certain patterns after induction of endometriosis in a mouse model Qiong-Hua Chen, Ph.D., Wei-Dong Zhou,

Pg and Ec LPS induced levels of soluble mediators from in cultures of individuals with and without T2D with periodontitis. Pg and Ec LPS induced levels.

Markers of lung injury in C57Bl/6 mice post IT-LPS.

Colocalisation of NLRP3 specks with cleaved interleukin (IL)-1β in bronchoalveolar lavage (BAL) macrophages, and nontypeable Haemophilus influenzae (NTHi)-stimulated.

Daniel R. Meldrum, MD, Brian D

BALB/c scid mice have higher levels of macrophage-stimulating cytokines in circulation compared with BALB/c control mice. BALB/c scid mice have higher.

Hypothesised conceptual framework of the association between lung and vascular events. Hypothesised conceptual framework of the association between lung.

Serum levels of angiopoietin-like protein 4 (ANGPTL4) according to patients with chronic obstructive pulmonary disease and controls without any lung disease.

Figure 1 Cytokine titers determined by the multiplex bead assay Plotted are cytokine titers (pg/mL) in CSF of patients with other noninflammatory neurologic.

Change from baseline in the severity of night-time cough and the frequency of night-time sputum production at week 12 in ACCORD COPD I.17 Data are reported.

Unstimulated levels of soluble mediators from in cultures of individuals with and without T2D with periodontitis. Unstimulated levels of soluble mediators.

Regulation of pentraxin-3 by antioxidants

Inducible nitric oxide synthase (iNOS), early growth response protein 2 (Erg2) and podoplanin expression on in vitro-generated inflammatory alveolar macrophages.

Comparison of the bronchoalveolar lavage fluid (BALF) levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients.

Patients’ pathways to Accident and Emergency (A&E)

Hosana G. Rodrigues, Marco Aurélio R

Concentration of inflammatory cytokines in epithelial lining fluid (ELF) were plotted for the normal control, smoker normal forced oscillation technique.

Romain Gallet et al. BTS 2016;1:14-28

Use of medication among chronic obstructive pulmonary disease (COPD) cases by age and place of residence among 1586 COPD cases. The dark grey bar represents.

Change from baseline in the severity of morning cough and severity of difficulty bringing up phlegm in the morning over the study period in the active-comparator.

Prevalence of chronic obstructive pulmonary disease (COPD) defined by different criteria by age, and place of residence. The dark grey bar represents ‘rural’

TLR2 expression is significantly higher in alveolar epithelium than in nasal epithelium, and correlates with IL-8 secretion. TLR2 expression is significantly.

Inflammatory stimuli increase angiopoietin-like protein 4 (ANGPTL4) gene and protein expression in human macrophages. Inflammatory stimuli increase angiopoietin-like.

Fig. 4. Acute lung injury in miR-223−/y mice.

Podoplanin expression on inflammatory alveolar macrophages (iAMs) regulates their immune function in vitro. Podoplanin expression on inflammatory alveolar.

Comparison of the serum levels of the three vascular endothelial growth factor (VEGF) types in healthy volunteers and patients with idiopathic pulmonary.

(A) Serum CRP levels. (A) Serum CRP levels. T2DM: n=6 per group. *p

Kaplan–Meier curves for the time until myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-positive conversion (A: MPO-ANCA, B: proteinase 3.

Comparative receiver operating characteristic (ROC) curves and the area under the curve (AUC) in association with 30-day mortality for severity scores.

Weight and cardiopulmonary parameter changes in C57Bl/6 mice post IT-LPS or PBS. Weight changes were assessed in C57Bl/6 instilled via IT route with 50 µg.

Receiver operating characteristic curves (ROC) for the metabolites between the systemic inflammatory response syndrome (n=15) and sepsis (n=35) groups.

Monitoring the induction of pro-inflammatory mediators and toll-like receptors (TLRs) following inhalation of AZD8848. Monitoring the induction of pro-inflammatory.

Proposed mechanisms for fibrointimal proliferation in pulmonary tumour thrombotic microangiopathy (PTTM). Proposed mechanisms for fibrointimal proliferation.

Worse eDiary scores are associated the more rescue inhaler usage and reduced step counts over both an individual day and 3-week summary period. Worse eDiary.

Mechanisms of virus-induced airway inflammation in chronic obstructive pulmonary disease (COPD). Mechanisms of virus-induced airway inflammation in chronic.

Effect of YopM on the transcription of pro-inflammatory cytokines in HL60-derived macrophages after stimulation with LPS. HL60 cells differentiated into.

Pharmacokinetics and efficacy of AZD8848 in the Brown Norway rat.

Plot of change in incremental shuttle walk test following pulmonary rehabilitation according to ACE (insertion/deletion) polymorphism. Plot of change in.

Changes in 6 min walk distance (6MWD) for combined pulmonary fibrosis and emphysema (CPFE) (n=15), and chronic obstructive pulmonary disease (COPD) (n=37).

(A) Energy and (B) protein intake/day during hospitalisation and in follow-up. (A) Energy and (B) protein intake/day during hospitalisation and in follow-up.

Screening test accuracy of the final risk score at a threshold of ≥2

COPD Action Plan adherence.

Induction of Interleukin-19 and Interleukin-22 After Cardiac Surgery With Cardiopulmonary Bypass Chung-Hsi Hsing, MD, Mei-Yi Hsieh, MS, Wei-Yu Chen,

Expression of genes related to inflammasome activation in peripheral blood mononuclear cell (PBMC) and bronchoalveolar lavage (BAL) macrophages. Expression.

Prevalence of chronic obstructive pulmonary disease (COPD) defined by different criteria by region. The dark grey bar represents ‘symptom-based COPD’,

Comparison of the serum and bronchoalveolar lavage fluid (BALF) levels of CCL21 among healthy volunteers and patients with idiopathic pulmonary fibrosis.

Baseline characteristics of the participants according to study group.

Induction of immune mediators and growth factors upon stimulation with pro-inflammatory cytokines. Induction of immune mediators and growth factors upon.

Cyclooxygenase (COX) independent chemopreventive mechanisms of non-steroidal anti-inflammatory drugs (NSAIDs). *Genes with a T cell factor 4 responsive.

Therapeutic administration of an anti-podoplanin antibody (α-PDPN) is beneficial during a mouse model of acute respiratory distress syndrome. Therapeutic.

Frequency distribution histograms of the Exacerbations of Chronic Pulmonary Disease Tool (EXACT) total, the COPD Assessment Test (CAT), the St George’s.

Receiver operating characteristic (ROC) curves for Saint George’s Respiratory Questionnaire (SGRQ) category scores predicting chronic obstructive pulmonary.

Presentation transcript:

Pulmonary cytokine expression in C57Bl/6 mice post IT-LPS. Pulmonary cytokine expression in C57Bl/6 mice post IT-LPS. C57Bl/6 mice were instilled via IT route with 50 µg LPS. BAL fluid was collected daily following IT-LPS and the expression of inflammatory cytokines assessed; CXCL1/KC (A), VEGF (B), MIP-2 (C), IL-6 (D), IL-1β (E) and TNFα (F). ANOVA, analysis of variance; BAL, bronchoalveolar lavage; IL, interleukin; IT-LPS, intratracheal lipopolysaccharide; MIP-2, macrophage-inflammatory protein-2; N.D., not detected; TNFα, tumor necrosis factors α; VEGF, vascular endothelial growth factor. Siân Lax et al. BMJ Open Resp Res 2014;1:e000014 ©2014 by British Thoracic Society