Fig. 5. Silencing of TAB2 mimics the effects of miR-155-5p on BSMCs

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Presentation transcript:

Fig. 5. Silencing of TAB2 mimics the effects of miR-155-5p on BSMCs Fig. 5. Silencing of TAB2 mimics the effects of miR-155-5p on BSMCs. (A) MTT assay was performed to evaluate the effects of TAB2 siRNA and miR-155-5p mimic on the proliferation of IL-13-induced BSMCs. Transfection with miR-155-5p mimic significantly inhibited cell proliferation. The same effect was found with TAB2 siRNA. (B) Transwell migration assay was performed to evaluate the effects of TAB2 siRNA and miR-155-5p mimic on the proliferation of IL-13-induced BSMCs. Transfection with miR-155-5p mimic significantly inhibited cell migration. The same effect was found with TAB2 siRNA. TAB2, transforming growth factor (TGF)-β-activated kinase 1/MAP3K7-binding protein 2; BSMC, bronchial smooth muscle cell; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; siRNA, small interfering RNA; IL, interleukin; ns, not significant. *P<0.05, †P<0.01, ‡P<0.001, §P<0.0001; ∥P<0.05 and ¶P<0.001 when compared with the control siRNA+IL-13 group. Fig. 5. Silencing of TAB2 mimics the effects of miR-155-5p on BSMCs. (A) MTT assay was performed to evaluate the effects of TAB2 siRNA and miR-155-5p mimic on the proliferation of IL-13-induced BSMCs. Transfection with miR-155-5p mimic significantly inhibited cell proliferation. The same effect was foun… Allergy Asthma Immunol Res. 2018 May;10(3):260-267. https://doi.org/10.4168/aair.2018.10.3.260