Difficulties improving ovarian functional recovery by microvascular transplantation and whole ovary vitrification Blandine Courbiere, M.D., Ludovic Caquant,

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Presentation transcript:

Difficulties improving ovarian functional recovery by microvascular transplantation and whole ovary vitrification Blandine Courbiere, M.D., Ludovic Caquant, M.D., Claire Mazoyer, M.S., Michel Franck, D.V.M., Jacqueline Lornage, M.D., Ph.D., Bruno Salle, M.D., Ph.D. Fertility and Sterility Volume 91, Issue 6, Pages 2697-2706 (June 2009) DOI: 10.1016/j.fertnstert.2008.03.012 Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Diagram of the experimental procedure, (A): Detail of surgical vascular anastomosis, (B): Orthotopic ovarian transplantation in ewe. Fertility and Sterility 2009 91, 2697-2706DOI: (10.1016/j.fertnstert.2008.03.012) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Detail of downstream lumbo-ovarian pedicle 14 months after ovarian cryopreservation and transplantation. A: Lumbo-ovarian artery, B: Lumbo-ovarian vein. Fertility and Sterility 2009 91, 2697-2706DOI: (10.1016/j.fertnstert.2008.03.012) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Histological comparison of primordial follicles between group 1 and group 2 (original magnification X 400). (A), Ovarian cortex aspect 16 months after transplantation (group 1). Black arrow indicates intact primordial follicle. (B), Ovarian cortex aspect 10 months after cryopreservation and transplantation (groupe 2). White arrow indicates atretic primordial follicle. Fertility and Sterility 2009 91, 2697-2706DOI: (10.1016/j.fertnstert.2008.03.012) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions