Volume 75, Issue 12, Pages 1253-1254 (June 2009) Arachidonic acid cytochrome P450 4F2 in hypertension: what can we learn from a transgenic mouse model?? Yiqiang Cai Kidney International Volume 75, Issue 12, Pages 1253-1254 (June 2009) DOI: 10.1038/ki.2009.82 Copyright © 2009 International Society of Nephrology Terms and Conditions
Figure 1 Model of CPY4F2 gene function. Increased expression of CYP4F2 that caused increased production of 20-HETE was associated with elevated blood pressure. However, the mechanism(s) underlying the link between increased 20-HETE and hypertension, and whether other factors contributed to the elevated blood pressure, remain unknown. Kidney International 2009 75, 1253-1254DOI: (10.1038/ki.2009.82) Copyright © 2009 International Society of Nephrology Terms and Conditions