Fig. 1. Mitochondrial internalization in cardiomyocytes.

Slides:



Advertisements
Similar presentations
inhibits BMP signalling.
Advertisements

Scanning electron microscopy analysis of EGK-I to -V chick embryos.
Distinct collagen structures in the upper and lower neonatal dermis (related to Fig 1)‏ Distinct collagen structures in the upper and lower neonatal dermis.
Fig. 6 Photoreceptor cell survival in the RCS rat retina after transplantation with hESC-RPE cell sheets. Photoreceptor cell survival in the RCS rat retina.
Fig. 6. crb_C mutant photoreceptor cells exhibit normal morphology.
Fig. 5. Prip silencing enhances the co-localization of GABARAP with insulin vesicles and β-tubulin.Co-localization of GABARAP (green) with insulin (red)
Fig. 1. Overview of the nervous system of the adult S. roscoffensis.
Fig. 2. Outline of the two types of stimulus sequences employed in the analysis.(A) Environment information stimuli; (B) adaptation stimuli. Outline of.
Fig. 8. In vitro effect of CMPs on adult DSS-treated stomach explants.
Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.
Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.
Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.
Fig. 5. Differentiated cells sort to the outer layer, regardless of E- or N-cadherin status.Wildtype and mutant ES cells were distinguished by GFP expression.
Fig. 4. Seeding density modulates cell shape in both cell types
Fig. 2. Proportion of motile objects and track length
The distribution of lamin C and emerin in lymphoblastoid cell lines.
Fig. 2. abu/pqn genes are expressed in the pharyngeal cuticle
Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.
Fig. 1. Prestin in mouse outer hair cells is localized along the lateral wall of the cell along with β-catenin and Na/K ATPase.Shown are cartoons of the.
Fig. 10. Ratiometric live imaging of di-4-ANEPPDHQ in growing pollen tubes.(A) Higher and lower membrane order distribution in control and BCD treated.
The effects of a dominant negative mutant of lamin B1 on lamin distribution in HeLa cells. The effects of a dominant negative mutant of lamin B1 on lamin.
Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.
Fig. 1. Loss of PC following INT depletion
Indirect fluorescence assay of N. gruberi cells.
Fig. 1. Morphological and growth characterization of hBMCs and hPDCs
Fig. 2. Salivary glands from RasV12-expressing larvae produce MMP1, release tissue fragments into the hemolymph and express apoptotic markers.Salivary.
Differentiation of neural crest cells into corneal endothelial cells
Fig. 6. LR phenotype of plastid translation-defective mutants with/without Spec. LR phenotype of plastid translation-defective mutants with/without Spec.
Fig. 4. Detection of dFMR1 mRNA in dFMRP granules by FISH
Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and -N media. Fcp1 CTD phosphatase affects a broad range of transcripts in the +N and.
Fig. 2. Ex vivo inducible knockout of PDCD2 in ESCs results in loss of S phase entry and increased p53.(A) Growth curve of inducible knockout and WT ESCs.
Fig. 5. The bulk of Cep135 localizes distantly from Sas-6 and STIL
Fig. 6. Comparison of Plk4 with Sas-6 localization
Fig. 6. Localization of Sma during growth and migration
Α-Catenin DKO cardiomyocytes exhibit increase proliferation on stiff ECM. (A) Representative images of neonatal cardiomyocytes cultured on different PA-FN.
Fig. 6. Effect of SAHA and ML on histone acetylation, BAX, and p21CDKN1A expression.PANC-1 and BxPC-3 cells were incubated for 48 hours with 5 µM.
Fig. 7. Lhx1-RNAi reduces the eye size
Fig. 2. Centrosomal proteins display distinct localizations and radial distances from centriole walls.U2OS cells were fixed and stained with the indicated.
Fig. 1. Effects on the tight junction barrier and permeability following doxorubicin and Herceptin treatment. Effects on the tight junction barrier and.
Fig. 3. Rnd proteins induce stronger responses in subconfluent endothelial cells.HUVECs were transfected with Rnd1, Rnd2, Rnd3 or GFP-encoding plasmids.
Fig. 7. Representative images of control (Cas9+GFP) and Cas9+gRNA+GFP co-injected embryos on day 4 of culture, showing nuclear-imported GFP (green) and.
Fig. 6. STK35 KO mice show ovary defects.
Fig. 4. CIZ1 reduces the impact of injury to the heart.
Statistical chart of significantly differentially expressed genes
Fig. 2. Sufficient rate of recombination in embryonic NSCs and NPCs of Emx1cre knock-in mice.(A) Breeding schemes to generate mice with the Emx1cre locus.
Fig. 1. Polarized F-actin cables in the Xenopus neural plate.
Fig. 1. Phenotypic characterisation of primary human tubular epithelial cells and human renal fibroblasts. Phenotypic characterisation of primary human.
Fig. 2. RFC3 function in chloroplasts.
Z-stack compressions showing triple labelling of different cell types in the gills of bowfin with antibodies for serotonin (5-HT, green) and HNK-1 (magenta),
Exo70 is recruited to the plasma membrane at sites of mechanical wounding. Exo70 is recruited to the plasma membrane at sites of mechanical wounding. NRK.
The actin organization and N-cadherin dynamics in migrating cells.
Single MTs can be resolved in subsections of SBF-SEM image stacks.
Fgfr3;4 mutant lungs display an increase in Mfap5, Igf1 and Fbn2 expression. Fgfr3;4 mutant lungs display an increase in Mfap5,Igf1and Fbn2 expression.
Fig. 2. iPSCs produce functional osteoblasts.
Ibm1 and edm2 mutants generate more stomatal divisions in the leaf epidermis. ibm1 and edm2 mutants generate more stomatal divisions in the leaf epidermis.
Global cell proliferation replenishes epidermal cells.
Altered intracellular distributions of acetylated α-tubulin, mitochondria and peroxisomes. Altered intracellular distributions of acetylated α-tubulin,
Fig. 2. Acetylation stiffens primary cilia.
Fig. 1. Rnd2 and Rnd3 induce stress fibres whereas Rnd1 reduces stress fibres in endothelial cells.(A) Rnd mRNAs are expressed in HUVECs. Total RNA was.
Fig. 6. RhoB is required for Rnd3-induced stress fibre formation
Fig. 4. Deletion of Baf60c in myocardium results in dilated chambers and impaired cardiac function. Deletion of Baf60c in myocardium results in dilated.
Fig. 5. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated.
EPLIN also plays a crucial role in the apical extrusion of RasV12-transformed cells. EPLIN also plays a crucial role in the apical extrusion of RasV12-transformed.
WT MARCH8, but not the CS mutant, specifically ubiquitinates and downregulates TfR. WT MARCH8, but not the CS mutant, specifically ubiquitinates and downregulates.
Histone crotonylation in kidney tubular cells.
2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. 2DG suppresses of lamellipodia.
Ezrin phenotypes in the MVID intestine.
Subcellular distribution of Mst4 and aPKCι in in vivo enterocytes.
Fig. 2. Immunocytochemical localization of NPC1 in alveolar type II cells. Isolated rat alveolar type II cells were fixed after 24 h in culture, double-labeled.
IFN treatment of human midgestation villous explants induces syncytial knot formation. IFN treatment of human midgestation villous explants induces syncytial.
Presentation transcript:

Fig. 1. Mitochondrial internalization in cardiomyocytes. Mitochondrial internalization in cardiomyocytes. (A) Representative florescent micrographs of isolated rat liver mitochondria labeled with pHrodo co-incubated with cardiomyocytes for 4 hour (middle panel) or 24 hours (right panel). Control cardiomyocytes (no mitochondria) are shown in the left panel. In all images the blue stain is DAPI; red, pHrodo labeled mitochondria, green is 488 phalloidin (f-actin). Scale bars are 25 µm. Results show internalization of transplanted mitochondria at 4 and 24 hours. (B) ATP content in cardiomyocytes: ATP content (nmol/103 cells) in control, no mitochondria (white bars) and cardiomyocytes co-incubated with mitochondria (black bars). (C) Mitochondrial uptake at 1, 4 and 24 hour co-incubation. The mean±sd for n = 5 experiments is shown. Results indicate that ATP content is significantly increased (p<0.05) in cardiomyocytes following 24 hours co-incubation with liver mitochondria. ATP standard luminescence; R2 = 0.9998. Statistical differences at p<0.05 vs. control is shown as *. Christina A. Pacak et al. Biology Open 2015;bio.201511478 © 2015. Published by The Company of Biologists Ltd