Treatment of infants coinfected with HIV-1 and cytomegalovirus with combination antiretrovirals and ganciclovir Akihiko Saitoh, Rolando M. Viani, Rachel.

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Presentation transcript:

Treatment of infants coinfected with HIV-1 and cytomegalovirus with combination antiretrovirals and ganciclovir Akihiko Saitoh, Rolando M. Viani, Rachel D. Schrier, Stephen A. Spector Journal of Allergy and Clinical Immunology Volume 114, Issue 4, Pages 983-985 (October 2004) DOI: 10.1016/j.jaci.2004.07.037 Copyright © 2004 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 Clinical courses (A-C) and LPAs (D) in 3 infants coinfected with CMV and HIV-1. A, Patient 1. B, Patient 2. C, Patient 3. Filled triangles indicate detectable plasma CMV DNA PCR results, and the numbers below are copy numbers (copies per milliliter). Open triangles indicate negative plasma CMV DNA PCR results. Dotted horizontal lines indicate undetectable plasma HIV-1 RNA of less than 400 copies/mL. ZDV, Zidovudine; 3TC, lamivudine; NFV, nelfinavir; D4T, stavudine; RTV, ritonavir. D, Simulation index (SI) of media was 1. Dotted horizontal line, SI of 3. An SI of greater than 3 was considered positive. HIV gag/p24/5, HIV p24 reagent; HIV Ag sup, HIV antigen supernatant; HSV, herpes simplex virus. Journal of Allergy and Clinical Immunology 2004 114, 983-985DOI: (10.1016/j.jaci.2004.07.037) Copyright © 2004 American Academy of Allergy, Asthma and Immunology Terms and Conditions