Fig. 1. Lack of Hmga1 and Hmga2 expression in A1/A2-KO mice

Slides:

Advertisements

Similar presentations

Tamoxifen induced deletion of FAK

Advertisements

Adamtsl2 targeting strategy and validation of inactivation.

Fig. 2. Effect of endurance training on gene expression, and protein content and activity in heart muscle. Effect of endurance training on gene expression,

Fig. 2. Spectral sensitivity of smolt melanophores and candidate photopigments involved in melanophore photosensitive processes.(A,B) Incident light triggered.

Fig. 1. Muscle-specific PITX1 over-expression in the Pitx1 transgenic mice.(A) Detection of Pitx1 mRNA expression in muscles of the Pitx1 transgenic mice.

TC-1 silencing sensitized A549 and SPC-A-1 cells to radiation therapy

Fig. 6. Comparison between the response against transformed tissues and capsule formation.At the cellular level the two responses share many similarities.

Fig. 2. p85β regulates cell adhesion

Fig. 4. Expression of miR-2 family mediates tissue growth of Hippo pathway.(A) Photomicrographs of adult wings of the indicated genotype. Expression of.

Fig. 2. Body weight and size analysis of A1/A2-KO mice

Fig. 5. Expression of either dFMRP or human FMRP does not induce eIF2α phosphorylation.(A) Analysis of eIF2α phosphorylation upon dFMRP expression. Expression.

Fig. 5. Onecut transcription factors are important for the correct generation of the mdDA neuronal population.(A) Schematic representation of the region.

Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.

TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.

Fig. 4. Increased adipocyte differentiation in Cbx7-KO ES cells

Fig. 4. The model of malate metabolism in fruit cells under different K level conditions. The model of malate metabolism in fruit cells under different.

Fig. 1. Body weight gain in Cbx7-KO mice

Fig. 3. Relative expression levels of ASNS to α-tubulin were dramatically increased when treating human cells with nocodazole and ASNase. Relative expression.

Fig. 7. E2F1 acetylation in A1/A2-KO MEFs

Fig. 7. SCF and IGF-1 accelerate fetal spleen erythropoiesis in vivo.

Fig. 1. IL-31 and IL-31R mRNA expression was upregulated in the asthma mouse model. IL-31 and IL-31R mRNA expression was upregulated in the asthma mouse.

Fig. 3. Characterization of unclassified cells (UCs).

Fig. 4. Targeted disruption of STK35 transcripts in mouse.

Expression data confirm and extend existing knowledge

Fig. 2. Ex vivo inducible knockout of PDCD2 in ESCs results in loss of S phase entry and increased p53.(A) Growth curve of inducible knockout and WT ESCs.

Fig. 5. GFP fluorescence colocalization of Gcn5.

Fig. 3. Computer-assisted sperm analyses (CASA) of epididymal sperm collected from wild-type (WT), miR-34b/c knockout (KO), miR-449 KO, and miR-34b/c;miR-449.

Fig. 6. Effect of SAHA and ML on histone acetylation, BAX, and p21CDKN1A expression.PANC-1 and BxPC-3 cells were incubated for 48 hours with 5 µM.

Fig. 6. CBX7 expression in adipocyte differentiation of adipose-derived stem cells.(A) The adipose-derived stem cells, ADS1, were analyzed for the capability.

Transcriptional profiling of selected genes by RT-PCR.

Fig. 2. Soluble sugar and organic acid levels with different K fertilization during fruit development. Soluble sugar and organic acid levels with different.

Fig. 4. BKA values for different species.

Fig. 1. Generation of WNK3 knockout mice

Fig. 7. Ror-GFP binds to Myc-tagged Wnts and Wnt receptors.

Fig. 1. TSA at 165 nM induces maximal acetylation of histone H3 and near-maximal acetylation of histone H4.Immunoblot analysis of acetylated histones H3.

Fig. 6. Increased oxidative stress in Nrf2-deficient cells

Fig. 6. STK35 KO mice show ovary defects.

Distribution and extent of expression.

Fig. 1. Nrf2 affects the mitochondrial membrane potential

Statistical chart of significantly differentially expressed genes

Fig. 4. Quantitative mRNA expression of two membrane-bound trehalase genes in Harmonia axyridis in response to starvation (0–72 h). Quantitative mRNA expression.

TWEAK increases histone crotonylation in kidney tubular cells.

Fig. 1. Expression of the five miRNAs encoded by two miRNA clusters in mouse sperm and oocytes.(A) qPCR analyses of levels of miR-16 (positive control),

Fig. 1. PARN is differentially expressed in breast cancer versus non-cancerous tissue/cells. PARN is differentially expressed in breast cancer versus non-cancerous.

Fig. 3. PLD2 and PARN overexpression affects PARN and PLD2 protein and gene expression. PLD2 and PARN overexpression affects PARN and PLD2 protein and.

Angiotensin-(1-7) activates the IGF-1/Akt signalling pathway during muscle disuse through the Mas receptor. Angiotensin-(1-7) activates the IGF-1/Akt signalling.

Fgfr3;4 mutant lungs display an increase in Mfap5, Igf1 and Fbn2 expression. Fgfr3;4 mutant lungs display an increase in Mfap5,Igf1and Fbn2 expression.

Gα12 is not required for hepatic cystogenosis induced by Pkd1 knockout

Smad3-KO adipose tissues have increased FA uptake and β-oxidation.

Angiotensin-(1-7) prevents the decreased myosin heavy chain levels and increased atrogin-1 and MuRF-1 expressions of muscle under disuse through the Mas.

Fig. 3. Effects of Tec on IL-1β-induced apoptosis in chondrocytes.

Generation and genotyping of Syk-AQL mice.

Analysis of mutant Best1 protein (Y227N) in testis and sperm function

The expression of two forms of N-cadherin.

Fig. 12. Overview of the molecular program essential to build mdDA neurons.The genes identified in this study (in red) have been added to the programming.

Fig. 2. Coupling of actin to cell–cell junctions requires α-catenin and is necessary for the establishment of the barrier.(A) Effect of Cytochalasin D.

Fig. 1. Expression of the five miRNAs encoded by two miRNA clusters in mouse sperm and oocytes.(A) qPCR analyses of levels of miR-16 (positive control),

Fig. 2. Acetylation stiffens primary cilia.

Fig. 1. Cell adhesion molecule expression and the aggregation of wildtype and mutant ES cells.(A) Wildtype (WT), E-cadherin null (9J), and N-cadherin null.

Fig. 5. Testis defects in STK35 KO mice.

Fig. 1. p85β localizes at adhesion plaques and associates with FAK

Fig. 3. Mean force and velocity during jumping

Fig. 1. Microarray analyses of genes whose expression is regulated by innervation during synaptogenesis.(A) Schematic drawings of the experimental design.

Table 1. Measurement of ring diameters of proteins localizing in ring-like patterns around centrioles.Consideration of the size of IgG (about 8 nm) raises.

Fig. 7. Nrf2-dependent enzyme activities in wild-type, Nrf2- and Keap1-deficient tissues.Hepatic (A,C,E) and cortical (B,D,F) enzyme activities of NQO1.

Fig. 5. Behaviours of the wild-types Oregon-R at two temperatures.

BCL-3 regulates expression of stemness-associated Wnt targets.

APLF regulates genes implicated in MET during the generation of iPSCs from fibroblasts. APLF regulates genes implicated in MET during the generation of.

VEGF expression in neoplastic and normal prostate tissue.

Fig. 4 Effects of hematopoietic restoration of TLR9 on adipose tissue inflammation and insulin resistance. Effects of hematopoietic restoration of TLR9.

Presentation transcript:

Fig. 1. Lack of Hmga1 and Hmga2 expression in A1/A2-KO mice Fig. 1. Lack of Hmga1 and Hmga2 expression in A1/A2-KO mice.(A) RT-PCR expression analysis of the Hmga1 gene in WT, A1-KO, A2-KO and A1/A2-KO spleen and kidney tissue. Lack of Hmga1 and Hmga2 expression in A1/A2-KO mice.(A) RT-PCR expression analysis of the Hmga1 gene in WT, A1-KO, A2-KO and A1/A2-KO spleen and kidney tissue. (B) RT-PCR expression analysis of Hmga2 gene in WT, A1-KO, A2-KO and A1/A2-KO testis tissue. (C) RT-PCR expression analysis of Hmga1 and Hmga2 genes in WT, A1-KO, A2-KO and A1/A2-KO MEFs at passage 4. G6PD gene expression was used as internal control. (D) Western blot analysis of Hmga1 and Hmga2 proteins in WT, A1-KO, A2-KO and A1/A2-KO protein extracted from MEFs at passage 4. γ-tubulin was used as loading control. Antonella Federico et al. Biology Open 2014;bio.20146759 © 2014. Published by The Company of Biologists Ltd