Leuteinizing hormone responses to leuprolide acetate discriminate between hypogonadotropic hypogonadism and constitutional delay of puberty Maria Elisabeth.

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Presentation transcript:

Leuteinizing hormone responses to leuprolide acetate discriminate between hypogonadotropic hypogonadism and constitutional delay of puberty Maria Elisabeth Street, M.D., Maria Antonietta Bandello, M.D., Cesare Terzi, M.D., Lourdes Ibañez, M.D., Lucia Ghizzoni, M.D., Cecilia Volta, M.D., Candida Tripodi, M.D., Raffaele Virdis, M.D. Fertility and Sterility Volume 77, Issue 3, Pages 555-560 (March 2002) DOI: 10.1016/S0015-0282(01)03213-7

Figure 1 Peak serum LH levels after leuprolide acetate stimulation in patients with hypogonadotropic hypogonadism (HH), constitutional delay of puberty (CDP), and in normal prepubertal and pubertal boys. Values are clearly different in HH and CDP: 2.8 IU/L is the upper limit in HH and 6.1 IU/L is the lower limit in CDP. Street. Stimulated LH discriminates delayed puberty. Fertil Steril 2002. Fertility and Sterility 2002 77, 555-560DOI: (10.1016/S0015-0282(01)03213-7)

Figure 2 Individual baseline (b) and stimulated LH (p) levels in boys with hypogonadotropic hypogonadism (HH) and constitutional delay of puberty (CDP) compared to mean basal and peak serum LH levels in normal prepubertal and pubertal males. Street. Stimulated LH discriminates delayed puberty. Fertil Steril 2002. Fertility and Sterility 2002 77, 555-560DOI: (10.1016/S0015-0282(01)03213-7)