Survival and telomere length of G2tert−/− zebrafish in a p53−/− background. Survival and telomere length of G2tert−/− zebrafish in a p53−/− background.

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Survival and telomere length of G2tert−/− zebrafish in a p53−/− background. Survival and telomere length of G2tert−/− zebrafish in a p53−/− background. (A) Larval survival curve (Kaplan-Meier representation) of four different genetic backgrounds. n, number of zebrafish per genotype. Statistical significance was assessed using the Log Rank test. (B) Mean telomeric fluorescence values of 24-hpf embryos (n≥100) from wild-type and mutant genetic backgrounds. Data are mean values ± s.e.m. and different letters (a, b) denote statistically significant differences between telomeric fluorescence values of each sample according to a Tukey test (P<0.05). (C) Kaplan-Meier representation of the survival of four genetic backgrounds. a.u.f., arbitrary units of fluorescence. Monique Anchelin et al. Dis. Model. Mech. 2013;6:1101-1112 © 2013. Published by The Company of Biologists Ltd