Pemphigus foliaceus associated with Hypericum perforatum

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Presentation transcript:

Pemphigus foliaceus associated with Hypericum perforatum Adrián Imbernón-Moya, MD, Fernando Burgos, MD, Elena Vargas-Laguna, MD, Eva Fernández-Cogolludo, MD, Antonio Aguilar- Martínez, MD, Miguel Ángel Gallego-Valdés, MD  JAAD Case Reports  Volume 2, Issue 4, Pages 326-328 (July 2016) DOI: 10.1016/j.jdcr.2016.06.008 Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Crusted patch on her lower neck. JAAD Case Reports 2016 2, 326-328DOI: (10.1016/j.jdcr.2016.06.008) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Pemphigus foliaceus. Scaly and crusted patches with erythematous edges on her upper back. JAAD Case Reports 2016 2, 326-328DOI: (10.1016/j.jdcr.2016.06.008) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Intraepidermal subcorneal blister with acantholytic keratinocytes and eosinophils. Inflammatory superficial dermal infiltrate composed of lymphocytes and eosinophils (Hematoxylin-eosin stain; original magnification: ×20). JAAD Case Reports 2016 2, 326-328DOI: (10.1016/j.jdcr.2016.06.008) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Direct immunofluorescence with deposits of IgG and C3 on keratinocytes' surface and along the dermo-epidermal junction. JAAD Case Reports 2016 2, 326-328DOI: (10.1016/j.jdcr.2016.06.008) Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions