Molecular diagnosis of nonaneurysmal infectious aortitis

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Presentation transcript:

Molecular diagnosis of nonaneurysmal infectious aortitis Shinji Kanemitsu, MD, Takatsugu Shimono, MD, Akiko Nakamura, Kiyohito Yamamoto, MD, Hideo Wada, MD, Hideto Shimpo, MD Journal of Vascular Surgery Volume 53, Issue 2, Pages 472-474 (February 2011) DOI: 10.1016/j.jvs.2010.09.012 Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 1 Abdominal computed tomography. Arrow indicates the thickened periaortic tissue. This does not indicate aneurysmal formation or rupture. Journal of Vascular Surgery 2011 53, 472-474DOI: (10.1016/j.jvs.2010.09.012) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

Fig 2 Pathologic findings of the surgical specimen of the aorta. A, Macroscopic image showing diffuse and tumorous thickening of the arterial wall. B, Microscopic image showing intense inflammatory change and fibrosis in the adventitia. Inflammatory cells are mainly lymphocytes, plasma cells, and eosinophils (hematoxylin and eosin, original magnification ×40). C, Immunostaining of IgG4 revealed numerous IgG4-positive plasma cells within the lesion (immunostaining of IgG4, ×400 original magnification). Journal of Vascular Surgery 2011 53, 472-474DOI: (10.1016/j.jvs.2010.09.012) Copyright © 2011 Society for Vascular Surgery Terms and Conditions