Class IV-S versus class IV-G lupus nephritis: Clinical and morphologic differences suggesting different pathogenesis Gary S. Hill, Michel Delahousse,

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Class IV-S versus class IV-G lupus nephritis: Clinical and morphologic differences suggesting different pathogenesis Gary S. Hill, Michel Delahousse, Dominique Nochy, Jean Bariaty Kidney International Volume 68, Issue 5, Pages 2288-2297 (November 2005) DOI: 10.1111/j.1523-1755.2005.00688.x Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 1 Class IV segmental proliferative lupus nephritis. Both glomeruli show segmental lesions, with a large segmental fibrinoid necrosis in the one on the left. PAS-Masson-silver stain, ×350 magnification. Kidney International 2005 68, 2288-2297DOI: (10.1111/j.1523-1755.2005.00688.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 2 Class IV global proliferative lupus nephritis. Both glomeruli show uniform diffuse endocapillary proliferation. Masson trichrome stain, ×350 magnification. Kidney International 2005 68, 2288-2297DOI: (10.1111/j.1523-1755.2005.00688.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 3 Survival from doubling of serum creatinine—Biopsy 1. Survivals are measured from the time of biopsy, but curves begin at the first event, censoring, or completion. Kidney International 2005 68, 2288-2297DOI: (10.1111/j.1523-1755.2005.00688.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 4 Survival from double of serum creatinine. Patients with persistent segmental or global proliferative lesions at biopsy 2. Survivals are measured from the time of biopsy, but curves begin at the first event, censoring, or completion. Kidney International 2005 68, 2288-2297DOI: (10.1111/j.1523-1755.2005.00688.x) Copyright © 2005 International Society of Nephrology Terms and Conditions