Fig. 3. Mutation of Y520 and Y667 result in increased delivery of prestin to the apical surface of MDCK cells.MDCK cells transiently transfected with wt.

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Scanning electron microscopy analysis of EGK-I to -V chick embryos.

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Fig. 5. Prip silencing enhances the co-localization of GABARAP with insulin vesicles and β-tubulin.Co-localization of GABARAP (green) with insulin (red)

Fig. 7. Vinculin recruitment enhances the efficiency of barrier formation.(A) TER measurements after a calcium switch in α-catenin-depleted MDCK cells.

Fig. 4. Clinically defined SMN mutants show alterations in the association with telomerase complex proteins. Clinically defined SMN mutants show alterations.

Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.

Fig. 3. Knockdown of cited3 results in increased cell death but it does not affect proliferation.Embryos that are injected with the control MO (A–C), cited3.

Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.

Fig. 1. Prestin in mouse outer hair cells is localized along the lateral wall of the cell along with β-catenin and Na/K ATPase.Shown are cartoons of the.

Fig. 7. Knockdown of Meis1 abolishes CR4. 2-GFP expression

Fig. 1. Exogenous folic acid and Folr1 rescues the function of a Rho-kinase binding mutation in Shroom3. Exogenous folic acid and Folr1 rescues thefunction.

Colocalization of the palmitoylation-deficient mutants of claudin-14 with the lysosomal membrane protein LAMP-2. Colocalization of the palmitoylation-deficient.

Fig. 1. Mitochondrial internalization in cardiomyocytes.

Fig. 4. Expression of p75NTR and time-course of TrkA autophosphorylation at the Y751 and Y490 sites in PC12-27 cells transfected with the vector, empty.

Fig. 1. Loss of PC following INT depletion

TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.

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Fig. 1. E-cadherin localizes in nano-scale clusters.

Fig. 1. γ-Tubulin localizes in close proximity to centriole walls in interphase but within an extended PCM meshwork in mitosis.U2OS cells were fixed and.

Fig. 2. DDR1 over-expression enhances collagen fibril reorganization

Fig. 8. Knockdown of Meis1 reduces the expression of Foxn4 and Lim1+2

Apical localization of PKA fusion constructs in infected and fully differentiated human airway epithelial cells. Apical localization of PKA fusion constructs.

Fig. 4. Detection of dFMR1 mRNA in dFMRP granules by FISH

Fig. 5. The bulk of Cep135 localizes distantly from Sas-6 and STIL

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Fig. 2. Soluble sugar and organic acid levels with different K fertilization during fruit development. Soluble sugar and organic acid levels with different.

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Characterization of anti-N-mPres.

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Fig. 2. iPSCs produce functional osteoblasts.

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Lysine residues in the cytoplasmic region of TfR are involved in the MARCH8-induced downregulation of TfR. Lysine residues in the cytoplasmic region of.

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Wrch-1 localizes to focal adhesions.

Misfolding mutations impair the BRCA1 nuclear aggregation in yeast and the BRCA1 nuclear localization in human cells. Misfolding mutations impair the BRCA1.

Fig. 5. Testis defects in STK35 KO mice.

Fig. 1. Rnd2 and Rnd3 induce stress fibres whereas Rnd1 reduces stress fibres in endothelial cells.(A) Rnd mRNAs are expressed in HUVECs. Total RNA was.

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mip120 null egg chambers have a condensed nurse cell DNA phenotype

Fig. 6. Bj mutants show stereocilia patterning defects and biliary duct (BD) malformations. Bj mutants show stereocilia patterning defects and biliary.

Fig. 5. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated.

EPLIN also plays a crucial role in the apical extrusion of RasV12-transformed cells. EPLIN also plays a crucial role in the apical extrusion of RasV12-transformed.

PtdIns(4,5)P2 dependence of TbEpsinR and TbCALM membrane targeting.

WT MARCH8, but not the CS mutant, specifically ubiquitinates and downregulates TfR. WT MARCH8, but not the CS mutant, specifically ubiquitinates and downregulates.

Fig. 4. Tetracycline-regulated expression of ClC-5 in the HEK293 cells stably expressing gastric H+,K+-ATPase.(A) Alignments of rat ClC-5, human ClC-5,

Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. Lack of Ctip2.

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Fig. 3. Mutation of Y520 and Y667 result in increased delivery of prestin to the apical surface of MDCK cells.MDCK cells transiently transfected with wt prestin YFP and the two constructs Y520Q prestin YFP, and Y667Q prestin YFP were fixed at 36 hours and stained with antibody to the apical marker GP130 (podohexin). Mutation of Y520 and Y667 result in increased delivery of prestin to the apical surface of MDCK cells.MDCK cells transiently transfected with wt prestin YFP and the two constructs Y520Q prestin YFP, and Y667Q prestin YFP were fixed at 36 hours and stained with antibody to the apical marker GP130 (podohexin). There is significant apical targeting of Y520Q and Y667Q evident in the serial X-Y sections along the z axis and the corresponding X-Z sections at the bottom. The bottom panel shows Pearson's correlation of prestin YFP and GP130 confirming absent apical targeting of the wild type construct and apical targeting of Y520Q and Y667Q. The mean Pearson's correlation values were: wt −0.027 (+/−0.011 SE, n = 7); Y520Q 0.105 (+/−0.035 SE, n = 5); Y667Q 0.17 (+/−0.063 SE, n = 11). The differences between wt prestin and Y520Q and wt prestin and Y667Q were significant. A one-way ANOVA (parametric) yielded a p value of <0.01 between wt prestin and Y520Q, and a p value of <0.001 between wt prestin and Y667Q. The scale bar is 5 microns. Yifan Zhang et al. Biology Open 2015;4:197-205 © 2015. Published by The Company of Biologists Ltd