Eric Mauri Michael Marquis Matthew Kasztejna Advised by: Dr. Wes Ely Delirium Detection Eric Mauri Michael Marquis Matthew Kasztejna Advised by: Dr. Wes Ely

Delirium Overview Brain’s form of organ dysfunction Impaired cognitive functioning Develops in over 80% of ICU patients Direct consequence of medical conditions, medication, toxin exposure, or a combination of all of these.

Delirium Demographics Occurs in 15-60% of general patients and most frequent complication of hospitalization in older patients Complicates 2-3 million people yearly. Involves over 17.5 million inpatient days. Over $4 billion in Medicare expenditures. Development of delirium selected as one of the top three most important areas for quality of care improvement in older adults.

How is it detected? Arousal Assessment Attention Assessment Ramsey Scale and Glasgow Coma Scale Attention Assessment Confusion Assessment Method (CAM) Acute onset of mental changes Inattention Disorganized thinking Alertness

Project Objectives Develop system that can continuously measure delirium in ICU patients Device must be small, cost-effective, comfortable, and practical Real-Time measurements, data storage, and analysis of information (software)

Current Work Researching companies for sleep detection systems on the market. Researching body signals indicating sleep status. Early design requirements as dictated by ICU requirements.

Future Work Review and evaluate preliminary findings. Set a meeting with neurology specialist Dr. Abhou-Kahalil at VUMC. Speak with sleep specialist Atul Malhotra at Harvard to review and evaluate the device.