SGLT2 inhibitor improves CV outcomes in diabetic patients with chronic kidney disease CANVAS programe subanalyses HR (95%CI): 0.65 (0.41-1.03) 0.71 (0.53-0.95) 0.95 (0.80-1.13) 0.84 (0.62-1.13) MACE: CV death, non-fatal myocardial infarction, or non-fatal stroke SGLT2: Sodium glucose co-transporter 2; CV: cardiovascular; MACE: major adverse CV events; CANVAS: CANagliflozin cardio Vascular Assessment Study Program; eGFR: estimated glomerular filtration rate; T2D: type 2 diabetes; CKD: chronic kidney disease; Neuen et al. Circulation 2018