Impact of Sublobar Resection on Pulmonary Function: Long-Term Results from American College of Surgeons Oncology Group Z4032 (Alliance) Michael S. Kent,

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Presentation transcript:

Impact of Sublobar Resection on Pulmonary Function: Long-Term Results from American College of Surgeons Oncology Group Z4032 (Alliance) Michael S. Kent, MD, Sumithra J. Mandrekar, PhD, Rodney Landreneau, MD, Francis Nichols, MD, Thomas A. DiPetrillo, MD, Bryan Meyers, MD, Dwight E. Heron, MD, MBA, David R. Jones, MD, Angelina D. Tan, BS, Sandra Starnes, MD, Joe B. Putnam, MD, Hiran C. Fernando, MD The Annals of Thoracic Surgery Volume 102, Issue 1, Pages 230-238 (July 2016) DOI: 10.1016/j.athoracsur.2016.01.069 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Patient Consolidated Standards of Reporting Trials diagram. (CT = computed tomography; Dlco% = percentage predicted diffusing capacity of the lung for carbon monoxide; FEV1%, = percentage predicted forced expiratory volume in 1 second; IRB = Institutional Review Board; NSCLC = non-small cell cancer.) The Annals of Thoracic Surgery 2016 102, 230-238DOI: (10.1016/j.athoracsur.2016.01.069) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Changes in median percentage predicted forced expiratory volume in 1 second (FEV1%; dark gray) and in diffusion capacity of the lung for carbon monoxide (Dlco%; light gray) over 24 months. The solid horizontal lines and dashed lines in the middle of each box indicate the median values for Dlco% and FEV1%, respectively, the top and bottom borders of the box mark the 75th and 25th percentiles, respectively, the whiskers mark the 90th and 10th percentiles, and the circles account for outliers. The Annals of Thoracic Surgery 2016 102, 230-238DOI: (10.1016/j.athoracsur.2016.01.069) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Changes in the percentage predicted diffusion capacity of the lung for carbon monoxide (Dlco%) and forced expiratory volume in 1 second (FEV1%) by tumor location in the middle upper lobe (light gray) and lower lobe (dark gray) over 24 months. The Annals of Thoracic Surgery 2016 102, 230-238DOI: (10.1016/j.athoracsur.2016.01.069) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Changes in percentage predicted diffusion capacity of the lung for carbon monoxide (Dlco%) and in forced expiratory volume in 1 second (FEV1%) by thoracotomy (light gray) or video-assisted thoracoscopic surgery (VATS; dark gray) approach over 24 months. The Annals of Thoracic Surgery 2016 102, 230-238DOI: (10.1016/j.athoracsur.2016.01.069) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions