Cigarette Smoking and the Colorectal Adenoma-Carcinoma Sequence

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Cigarette Smoking and the Colorectal Adenoma-Carcinoma Sequence Julian A. Abrams, Mary Beth Terry, Alfred I. Neugut  Gastroenterology  Volume 134, Issue 2, Pages 617-619 (February 2008) DOI: 10.1053/j.gastro.2007.12.015 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 The odds ratio (OR) overestimates the relative risk (RR) to a greater degree when the outcome is common. If smoking increases the risk of adenoma formation and does not influences other steps of neoplastic progression, then the RR for adenomas will equal the RR for colorectal cancer (CRC). The OR, on the other hand, will be greater for adenomas than for CRC. Gastroenterology 2008 134, 617-619DOI: (10.1053/j.gastro.2007.12.015) Copyright © 2008 AGA Institute Terms and Conditions

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