Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: A randomized, double-blind, placebo-controlled study Giovanni B. Pajno,

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Presentation transcript:

Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: A randomized, double-blind, placebo-controlled study Giovanni B. Pajno, MD, Lucia Caminiti, MD, Daniela Vita, MD, Giovanni Barberio, MD, Giuseppina Salzano, MD, Fortunato Lombardo, MD, Giorgio Walter Canonica, MD, Giovanni Passalacqua, MD Journal of Allergy and Clinical Immunology Volume 120, Issue 1, Pages 164-170 (July 2007) DOI: 10.1016/j.jaci.2007.04.008 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Change from baseline (Δ SCORAD) in the SLIT and placebo groups at the different time points. ∗Significant differences between groups. Journal of Allergy and Clinical Immunology 2007 120, 164-170DOI: (10.1016/j.jaci.2007.04.008) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 VAS scores (median, range) in the SLIT and placebo groups at the different time points. The box represents the range. The median is marked as a thick line. Journal of Allergy and Clinical Immunology 2007 120, 164-170DOI: (10.1016/j.jaci.2007.04.008) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Change from baseline (Δ SCORAD) in the SLIT and placebo groups at the different time points. The patients are subdivided according to AD severity (A, mild-moderate; B, severe). ∗Significant differences. Journal of Allergy and Clinical Immunology 2007 120, 164-170DOI: (10.1016/j.jaci.2007.04.008) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 VAS scores (median, range) in the SLIT and placebo groups at the different time points. The box represents the range. The median is marked as a thick line. Patients are subdivided according to AD severity (A, mild-moderate; B, severe). ∗Significant differences. Journal of Allergy and Clinical Immunology 2007 120, 164-170DOI: (10.1016/j.jaci.2007.04.008) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 5 Total drug consumption (means, SEMs) in the whole population, in mild-moderate AD, and in severe AD. Journal of Allergy and Clinical Immunology 2007 120, 164-170DOI: (10.1016/j.jaci.2007.04.008) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions