Intimal Hyperplasia and Expression of Transforming Growth Factor-β1 in Saphenous Veins and Internal Mammary Arteries Before Coronary Artery Surgery Reinhard.

Slides:

Advertisements

Similar presentations

Volume 144, Issue 1, Pages 7-14 (May 1999)

Advertisements

Mauer Biscotti, MD, Matthew Bacchetta, MD

Increased incidence of acute ascending aortic dissection with off-pump aortocoronary bypass surgery? Olivier Chavanon, MD, Michel Carrier, MD, Raymond.

High-flow gas insufflation to facilitate MIDCABG: effects on coronary endothelium William R Burfeind, MD, Francis G Duhaylongsod, MD, Brian H Annex, MD,

Hypercholesterolemia Impairs the Myocardial Angiogenic Response in a Swine Model of Chronic Ischemia: Role of Endostatin and Oxidative Stress Munir Boodhwani,

Off-Pump Surgery for Multiple Coronary Artery Fistulas With Aneurysm

Comparative Evaluation of Multimedia Driven, Interactive, and Case-Based Teaching in Heart Surgery Reinhard Friedl, MD, Helmut Höppler, MD, Karl Ecard,

Bronchial Carcinoid Secreting Insulin-Like Growth Factor-1 With Acromegalic Features Joseph D. Phillips, MD, Anjana Yeldandi, MD, Mathew Blum, MD, Alberto.

Chia-Cheng Kuo, MD, Chung-Hsi Hsing, MD, PhD, Bor-Chih Cheng, MD

Atherosclerotic aneurysm formation in an in situ saphenous vein graft

Gene transfer to coronary artery bypass conduits

Philip J Wolfson, MD The Annals of Thoracic Surgery

Arteriotomy closure by glued patch in the porcine carotid artery

The Annals of Thoracic Surgery

Histologic evidence of the safety of endoscopic saphenous vein graft preparation Dan M Meyer, MD, Thomas E Rogers, MD, Michael E Jessen, MD, Aaron S Estrera,

Evidence of Nitric Oxide Produced by the Internal Mammary Artery Graft in Venous Drainage of the Recipient Coronary Artery Ferenc I. Tarr, MD, PhD, Mária.

Giant Costal Osteochondroma in a Man With Multiple Exostoses

Mortality on the waiting list for coronary artery bypass grafting: incidence and risk factors Helena Rexius, MD, Gunnar Brandrup-Wognsen, MD, PhD, Anders.

Right internal thoracic artery or saphenous vein grafting

Abdominal Aorta Aneurysms in Children: Single-Center Experience of Six Patients Caisheng Ye, MD, PhD, Henghui Yin, MD, PhD, Ying Lin, MD, PhD, Li Zhou,

The Society of Thoracic Surgeons Thoracic Surgery Practice and Access Task Force: 2014 Workforce Report John S. Ikonomidis, MD, PhD The Annals of Thoracic.

Pulmonary Lymphangioma

Hao G. Nguyen, MD, PhD, Amit Korach, MD, Chey Collura, MA, Benjamin R

Richard Gitter, Chris M. Cate, Kenneth Smart, G.Kimble Jett

Ho Young Hwang, MD, Jun Sung Kim, MD, Ki-Bong Kim, MD, PhD

Right Gastroepiploic Artery Graft for Myocardial Revascularization: Prevalence of Atherosclerosis and Availability as a Conduit Kwang Ree Cho, MD, PhD,

Treatment of a Nonhealing Saphenous Vein Harvest Graft with Treprostinil Sodium Dianne Zwicke, MD, Brian Buggy, MD, Don Lobacz, BSN, Kristan Rollins,

Expression and Function of Endothelial Nitric Oxide Synthase Messenger RNA and Protein Are Higher in Internal Mammary Than in Radial Arteries Guo-Wei.

Robotic-Assisted Coronary Artery Bypass on a Beating Heart: Initial Experience and Implications for the Future William F. Turner, MD, John H. Sloan,

Prox-1: A Specific and Sensitive Marker for Lymphatic Endothelium in Normal and Diseased Human Tissues Eumenia Costa da Cunha Castro, MD, PhD, Csaba.

Surgical Resection of a Giant Coronary Aneurysm

Nodular Lymphoid Hyperplasia of the Lung: A Very Rare Disease Entity

Avoidable Errors in Cardiac Surgery: Anastomosis of the Left Internal Mammary Artery to a Vein Deepak Banerjee, MD, Daniel Fusco, MD, Jeffrey Green,

Pulmonary artery aneurysm in a pregnant woman

Origins of the Cardiothoracic Surgery Network (CTSNet)

Who Do You Say You Are? The Annals of Thoracic Surgery

Which Patients Benefit From Stentless Aortic Valve Replacement?

Visceral pleural involvement in nonsmall cell lung cancer: prognostic significance Toshihiro Osaki, MD, PhD, Akira Nagashima, MD, PhD, Takashi Yoshimatsu,

Heparin-induced thrombocytopenia and cardiac surgery

Use of Amiodarone After Major Lung Resection

Anomalous Origin of Left Pulmonary Artery From Left Subclavian Artery

Inhibitory effect of methylene blue-induced photooxidation on intimal thickening of vein graft Ke-Xiang Liu, MD, Fumio Yamamoto, MD, Satoshi Sekine,

Oh, father, where art we? Left internal mammary artery with greater saphenous vein grafts still rules surgical coronary revascularization after 30 years

Heavy Smoking Before Coronary Surgical Procedures Affects the Native Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Gene Expression in Saphenous.

Expression of Endothelin-1 and Constitutional Nitric Oxide Synthase Messenger RNA in Saphenous Vein Endothelial Cells Exposed to Arterial Flow Shear Stress

Morphologic characteristics of varicose veins: possible role of metalloproteinases Kenneth J Woodside, MD, Mingdao Hu, MD, Ann Burke, MS, Maki Murakami,

Effects of intracoronary shunts on coronary endothelial coating in the human beating heart Herbert B Hangler, MD, Kristian Pfaller, PhD, Elfriede Ruttmann,

Editorial Board, January 2010

Severe Two-Vessel Ostial Stenosis of the Main Coronary Arteries in a Patient With Transposition of the Great Arteries After an Arterial Switch Operation

Electron Microscopic Evaluation of Internal Thoracic Artery Endothelial Morphology in Diabetic Coronary Bypass Patients Vedat Bakuy, MD, Orcun Unal,

Low-Grade Intimal Hyperplasia in Internal Mammary and Right Gastroepiploic Arteries as Bypass Grafts Jacques A.M van Son, Volkmar Falk, Thomas Walther,

Histological confirmation of healing of gastrobronchial fistula using a muscle flap Manabu Okuyama, MD, Reijiro Saito, MD, Satoru Motoyama, MD, Michihiko.

Pressure distension stimulates the expression of endothelial adhesion molecules in the human saphenous vein graft Massimo Chello, MD, Pasquale Mastroroberto,

Atrial Natriuretic Peptide-Induced Release of Cyclic Guanosine Monophosphate by Coronary Bypass Grafts Johannes Bonatti, MD, Wolfgang Dichtl, MD, Erika.

Graft to Coronary Artery Shunt During Off-Pump Coronary Artery Bypass Grafting Hiroshi Iida, MD, PhD, Hideaki Mori, MD, PhD, Yoshio Sudo, MD, PhD, Yasuyuki.

Minimally Invasive Axillary– Coronary Artery Bypass

Peter Pecher, MD, Bernd A Schumacher, MD

Kagami Miyaji, MD, Randall K Wolf, MD, John B Flege, MD

Invited Commentary The Annals of Thoracic Surgery

Robert Lee Replogle, September 30, 1931–May 9, 2016

Max B. Mitchell, MD, David N. Campbell, MD

Morphology and histology of human and canine internal thoracic arteries Tadahiro Sasajima, MD, Vishwanath Bhattacharya, MD, Moses Hong-De Wu, MD, Qun.

Håvard Nordgaard, MD, Nicola Vitale, MD, PhD, Rune Haaverstad, MD, PhD

Permanent wall stretching in porcine coronary and internal mammary arteries Carolien J van Andel, MS, PhD, Peter V Pistecky, MS, Paul F Gründeman, MD,

Coronary Ostial Stenosis After Aortic Valve Replacement, Revisited

Increased Rehospitalization Rate After Coronary Bypass Operation for Acute Coronary Syndrome: A Prospective Study in 200 Patients Staffan Bjessmo, MD,

Dumbor L. Ngaage, MD, FRCS (C-Th), Michael E. Cowen, FRCS

Surgery for Anomalous Aortic Origin of the Coronary Artery

The Annals of Thoracic Surgery

The Impact of New Technology on Cardiothoracic Surgical Practice

Presentation transcript:

Intimal Hyperplasia and Expression of Transforming Growth Factor-β1 in Saphenous Veins and Internal Mammary Arteries Before Coronary Artery Surgery Reinhard Friedl, MD, Jun Li, MD, Bernd Schumacher, MD, Hartmut Hanke, MD, Johannes Waltenberger, MD, Andreas Hannekum, MD, Sylvia Stracke, MD The Annals of Thoracic Surgery Volume 78, Issue 4, Pages 1312-1318 (October 2004) DOI: 10.1016/j.athoracsur.2004.02.066

Fig 1 (A) Human saphenous vein (HSV) with a circumferential intimal hyperplasia and an increased staining for transforming growth factor-β1 (TGF-β1) in the endothelial, intimal, and medial layer (original magnification ×5; inset ×20). (B) A normal native HSV without any tissue between the endothelium and the internal elastic membrane. Transforming growth factor-β1 staining in the medial layer is stronger than in the normal native internal mammary artery ([IMA] original magnification ×5; inset ×20). (C) Internal mammary artery with a focal intimal hyperplasia and an increased staining for TGF-β1 in the endothelial, intimal, and medial layer (original magnification ×5; inset ×20). (D) Normal IMA with no stromal or cellular tissue between the endothelium and the internal elastic membrane. Staining for TGF-β1 is weak (original magnification ×5; inset ×20). The Annals of Thoracic Surgery 2004 78, 1312-1318DOI: (10.1016/j.athoracsur.2004.02.066)

Fig 2 The incidence of intimal hyperplasia (IH) was significantly higher in native human saphenous vein (HSV) compared with native internal mammary artery (IMA). The Annals of Thoracic Surgery 2004 78, 1312-1318DOI: (10.1016/j.athoracsur.2004.02.066)