Jaime Ferro, M. D. , Ma. Carmen Martínez, M. D. , Coral Lara, M. D

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Improved accuracy of hysteroembryoscopic biopsies for karyotyping early missed abortions Jaime Ferro, M.D., Ma.Carmen Martínez, M.D., Coral Lara, M.D., Antonio Pellicer, M.D., José Remohí, M.D., Vicente Serra, M.D. Fertility and Sterility Volume 80, Issue 5, Pages 1260-1264 (November 2003) DOI: 10.1016/S0015-0282(03)02195-2

FIGURE 1 (A) Gestational sac prominence within the uterine cavity (6 weeks). (B) Extracelomic space from a 6-week embryonic partial mole (confirmed on histology). Karyotype: 47,XY,+18. The vesicular appearance of the hydropic chorionic villi, surrounded by a hyperemic tissue, is seen through the transparent chorionic membrane. The embryo within the amniotic cavity, the yolk stalk with an abnormal vesicular degeneration, and a small portion of the transparent yolk sac are viewed in perspective. (C) Normal appearance of chorionic villi within the chorion frondosum (8 weeks). Karyotype: 46,XY. (D) Regular chorionic villi alternating with others of edematous appearance (7 weeks). Karyotypes: 46,XX (embryo) and 46,XX,del (10p) (chorion). Ferro. Hysteroembryoscopic biopsies. Fertil Steril 2003. Fertility and Sterility 2003 80, 1260-1264DOI: (10.1016/S0015-0282(03)02195-2)