2003-2004 Nervous System Pharmacology Review 19 July 2019 9:05 PM

Adrenocorticotropin (ACTH) Anterior pituitary hormone Anticonvulsant Stimulates synthesis and release of cortisol

Opioid General anaesthetic Intravenous anaesthetic Alfentanil Opioid General anaesthetic Intravenous anaesthetic

Antiviral Antiparkinson Amantadine Antiviral Antiparkinson Treatment of Influenza A Inhibits replication at the stage of uncoating Inhibits dopamine release

Tricyclic antidepressant (TCA) Amitriptyline Tricyclic antidepressant (TCA)

Indirect sympathomimetic Drug of abuse ADD treatment Stimulant Amphetamine Indirect sympathomimetic Drug of abuse ADD treatment Stimulant

Atropine Anticholinergic Antimuscarinic Treatment for bradycardia, diarrhea, cholinesterase poisoning

Skeletal muscle relaxant Anxiolytic Baclofen Skeletal muscle relaxant Anxiolytic GABAB agonist

Anticholinergic Antiparkinson Muscarinic receptor antagonist Benztropine Anticholinergic Antiparkinson Muscarinic receptor antagonist

Muscarinic agonist Induces defecation and urination Bronchoconstrictor Bethanecol Cholinomimetic Muscarinic agonist Induces defecation and urination Bronchoconstrictor

Dopamine (D2) agonist Inhibits prolactin release Bromocriptine Antiparkinson Dopamine (D2) agonist Inhibits prolactin release

Second generation antidepressant Brupropion Second generation antidepressant

Buprenorphine Opioid Partial agonist

Sedative/hypnotic Anxiolytic Buspirone Sedative/hypnotic Anxiolytic

 receptor partial agonist or antagonist Butorphanol Opioid Analgesic  receptor partial agonist or antagonist

Carbamazepine Anticonvulsant

Peripheral dopa decarboxylase inhibitor Carbidopa Antiparkinson Peripheral dopa decarboxylase inhibitor

NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor Celecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

Chloral hydrate Sedative/Hypnotic General anaesthetic Acts on GABAA receptor complex Similar to barbiturates

Chlordiazepoxide Sedative/hypnotic Anxiolytic Benodiazepine Acts on GABAA receptor complex

Chlorpromazine Antipsychotic Phenothiazine

Clozapine Antipsychotic

Cocaine Indirect sympathomimetic Drug of abuse Topical anaesthetic Stimulant Local anaesthetic

Codeine Opioid Analgesic Weak agonist

Dantrolene Skeletal muscle relaxant Ryanodine receptor antagonist Treatment for malignant hyperthermia

Monoamine oxidase B inhibitor (MAO-I) Potentiates effects of L-Dopa Deprenyl/selegiline Antiparkinson Monoamine oxidase B inhibitor (MAO-I) Potentiates effects of L-Dopa

Tricyclic antidepressant (TCA) Desipramine Tricyclic antidepressant (TCA)

Dextromethorphan Opioid Antitussive

Diazepam Sedative/hypnotic Anxiolytic Anticonvulsant Benzodiazepine Acts on GABAA receptor complex

Diphenoxylate docusate Antidiarrheal Opiate

Enflurane General anaesthetic Inhaled anaesthetic

Peripheral catechol-o- methyltransferase inhibitor Entacapone Antiparkinson Peripheral catechol-o- methyltransferase inhibitor

Amphetamine-like stimulant Ephedra (Ma Huang) Dietary supplement Amphetamine-like stimulant

Ethanol Drug of abuse Sedative

Ethosuximide Anticonvulsant

Intravenous anaesthetic Etomidate General anaesthetic Intravenous anaesthetic

Fentanyl Opioid Analgesic  receptor agonist

Benzodiazepine antagonist Acts on GABAA receptor complex Flumazenil Benzodiazepine antagonist Acts on GABAA receptor complex

Selective serotonin reuptake inhibitor (SSRI) Fluoxetine Antidepressant Selective serotonin reuptake inhibitor (SSRI)

Benzodiazepine Acts on GABAA receptor complex Flurazepam Sedative/Hypnotic Benzodiazepine Acts on GABAA receptor complex

Treatment of Alzheimer symptoms Ginko biloba Dietary supplement Treatment of Alzheimer symptoms

Glutethimide Sedative/Hypnotic

Haloperidol Antipsychotic

Halothane General anaesthetic Inhaled anaesthetic

Heroin Drug of abuse Opioid

Indirect sympathomimetic Tricyclic antidepressant (TCA) Imipramine Indirect sympathomimetic Tricyclic antidepressant (TCA) Antimicturant

Isoflurane General anaesthetic Inhaled anaesthetic

Stress relief and treatment of insomnia Kava kava Dietary supplement Stress relief and treatment of insomnia

General anaesthetic Drug of abuse Ketamine General anaesthetic Drug of abuse Sedative

Levodopa Antiparkinson Dopamine precursor

Lidocaine Class I antiarrhythmic Local anaesthetic Na+ channel blocker (activated and inactivated channels)

Used to treat manic/depressive disorder Lithium Antidepressant Used to treat manic/depressive disorder

Loperamide Antidiarrheal Opiate

Lorazepam Anxiolytic Anticonvulsant Benzodiazepine Acts on GABAA receptor complex

Lysergic acid diethylamide (LSD) Drug of abuse Hallucinogen

Marijuana Drug of abuse Cannabinoid

Meperidine Opioid analgesic  receptor agonist

Mepivacaine Local anaesthetic

Sedative/hypnotic Anxiolytic Meprobamate Sedative/hypnotic Anxiolytic

Metamphetamine Drug of abuse Stimulant

Methadone Opioid  receptor agonist

Morphine Opioid Analgesic  receptor agonist

Nalbuphine Opioid antagonist  receptor antagonist

Nalmefene Opioid antagonist

Nalorphine Opioid antagonist

Naloxone Opioid antagonist

Naltrexone Opioid antagonist

Neostigmine Anticholinesterase Vasodilator Treatment for myaesthenia gravis Promotes defecation and urination Bronchoconstrictor

Cholinomimetic Drug of abuse Nicotine Cholinomimetic Drug of abuse Nicotinic receptor agonist (skeletal muscle contraction) Stimulant Smoking cessation medication

Nitrous oxide General anaesthetic Inhaled anaesthetic

Tricyclic antidepressant (TCA) Nortriptyline Tricyclic antidepressant (TCA)

Oxazepam Sedative/hypnotic Anxiolytic Benzodiazepine Acts on GABAA receptor complex

Muscarinic receptor antagonist Prevents urination Oxybutinin Anticholinergic Muscarinic receptor antagonist Prevents urination

Oxycodone Analgesic Opioid agonist

Paraldehyde Sedative/Hypnotic

 receptor partial agonist or antagonist Pentazocine Opioid analgesic  receptor partial agonist or antagonist

Pentobarbital Sedative/Hypnotic Barbiturate

Phencyclidine (PCP) Drug of abuse Hallucinogen

Sedative/Hypnotic Anticonvulsant Phenobarbital Sedative/Hypnotic Anticonvulsant Barbiturate

Phenytoin Anticonvulsant Class I antiarrhythmic Na+ channel blocker (inactivated channels)

Dopamine agonist (non-ergot) Pramipexole Antiparkinson Dopamine agonist (non-ergot)

Primidone Anticonvulsant

Procaine Local anaesthetic

Intravenous anaesthetic Propofol General anaesthetic Intravenous anaesthetic

Resperidone Antipsychotic

Dopamine agonist (non-ergot) Ropinirole Antiparkinson Dopamine agonist (non-ergot)

Selective serotonin reuptake inhibitor (SSRI) Sertraline Antidepressant Selective serotonin reuptake inhibitor (SSRI)

Sildenafil Vasodilator Promotes erection

St. John’s Wort Dietary supplement Antidepressant

Opioid General anaesthetic Intravenous anaesthetic Sufentanil Opioid General anaesthetic Intravenous anaesthetic

Benzodiazepine Acts on GABAA receptor complex Temazepam Sedative/Hypnotic Benzodiazepine Acts on GABAA receptor complex

Tetracaine Local anaesthetic

Ultra-short-acting barbiturate Thiopental General anaesthetic Ultra-short-acting barbiturate

Thioridazine Antipsychotic Phenothiazine

Thiothixene Antipsychotic

Muscarinic receptor antagonist Prevents urination Tolterodine Anticholinergic Muscarinic receptor antagonist Prevents urination

Monoamine oxidase inhibitor (MAO-I) Tranylcypromine Antidepressant Monoamine oxidase inhibitor (MAO-I)

Benzodiazepine Acts on GABAA receptor complex Triazolam Sedative/Hypnotic Benzodiazepine Acts on GABAA receptor complex

Trifluoperazine Antipsychotic Phenothiazine

Trihexyphenidyl Antiparkinson Antimuscarinic

Valproic acid Anticonvulsant

Irreversible GABA aminotransferase inhibitor Vigabatrin Anticonvulsant Irreversible GABA aminotransferase inhibitor

Zolpidem Sedative/Hypnotic Non-benzodiazepine