Got Guts? Need Nerve! Gastroenterology Liping Su, Jerrold R. Turner  Gastroenterology  Volume 132, Issue 4, Pages 1615-1618 (April 2007) DOI: 10.1053/j.gastro.2007.03.015 Copyright © 2007 AGA Institute Terms and Conditions

Figure 1 Intestinal epithelial barrier regulation by glial products. Enteric glia encircle enteric neurons as neuronal processes extend from Auerbach’s and Meissner’s plexi to the mucosa. As shown in the inset, these glia release many products, including glial-derived neurotrophic factor and GSNO. Savidge et al. show that GSNO can prevent epithelial barrier loss, perhaps by signaling to the epithelial tight junction. Gastroenterology 2007 132, 1615-1618DOI: (10.1053/j.gastro.2007.03.015) Copyright © 2007 AGA Institute Terms and Conditions