Low serum osteoprotegerin levels in premenopausal infertile women with low bone density: an association of relevance? John M. Norian, MD., Gohar Zeitlian,

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Low serum osteoprotegerin levels in premenopausal infertile women with low bone density: an association of relevance? John M. Norian, MD., Gohar Zeitlian, M.D., Goli Adel, B.S., Ruth G. Freeman, M.D., Nanette F. Santoro, M.D., Lubna Pal, M.B.B.S., MRCOG, M.S. Fertility and Sterility Volume 91, Issue 2, Pages 542-548 (February 2009) DOI: 10.1016/j.fertnstert.2007.11.089 Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Premenopausal infertile women show an inverse correlation between serum osteoprotegerin (OPG) and receptor activator of NF-κB ligand (RANk-L) levels. Fertility and Sterility 2009 91, 542-548DOI: (10.1016/j.fertnstert.2007.11.089) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Prevalence of low bone mineral density (BMD) in infertile women is shown across tertiles for osteoprotegerin (OPG) levels. A statistically significantly higher prevalence of low BMD is noted in women with serum OPG levels in the lowest OPG tertile (compared with the middle to highest tertiles). Fertility and Sterility 2009 91, 542-548DOI: (10.1016/j.fertnstert.2007.11.089) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions