A: Kaplan-Meier curves depicting the cumulative probability of CVE in patients with low (<−17.1 dB; n = 42) and high (≥−17.1 dB; n = 43) Calibrated-IBS values. A: Kaplan-Meier curves depicting the cumulative probability of CVE in patients with low (<−17.1 dB; n = 42) and high (≥−17.1 dB; n = 43) Calibrated-IBS values. The risk for CVE was significantly higher in the subjects with low Calibrated-IBS values as compared with those with high Calibrated-IBS values (P = 0.004, log-rank test). B: Kaplan-Meier curves depicting the cumulative probability of CVE in patients with large (>1.3 mm; n = 43) and small (≤ 1.3 mm; n = 42) plaque thickness values. Although the risk for CVE was relatively higher in the subjects with large plaque thickness as compared with those with small ones, it did not reach statistical significance (P = 0.148, log-rank test). Naoto Katakami et al. Dia Care 2012;35:2640-2646 ©2012 by American Diabetes Association