Tubulin PTM types and sites.

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Tubulin PTM types and sites. Tubulin PTM types and sites. Shown are the well-characterized post-translational modifications that act on tubulin and the enzymes that are responsible for these modifications. Most of the modifications occur at the C-terminal tail (CTT) domains of α- and β-tubulin. Ac, acetylated lysine; E, glutamic acid; G. glycine; Met, methylated glutamic acid; Δ2, proteolytic removal of the penultimate C-terminal amino acid. Dorota Wloga, and Jacek Gaertig J Cell Sci 2010;123:3447-3455 © 2010.