Fig. 2 Views of the Pincer-FATKIN interface and the dimer interface.

Slides:

Advertisements

Similar presentations

How IRE1 Reacts to ER Stress

Advertisements

A Drug-Drug Interaction Crystallizes a New Entry Point into the UPR

Crystal structure of STAT6CF-N3 complex and its comparison with STAT6CF-N4 complex structure. Crystal structure of STAT6CF-N3 complex and its comparison.

Fig. 5 In vivo MIP imaging of lipid and protein in C. elegans.

Fig. 1 Upward emission functions used to compute the maps.

Fig. 1 Dynamics of crowded solutions probed by NSE.

Fig. 2 New bathymetry. New bathymetry. (A) Uninterpreted bathymetry. Black lines represent seismic profiles acquired. The white line shows the position.

Fig. 4 Estimations of nonlinear functionals of a single-qubit state with the quantum Fredkin gate. Estimations of nonlinear functionals of a single-qubit.

Fig. 2 APT reconstructed volumes of human dental enamel HAP nanowires showing intergranular Mg-rich ACP. APT reconstructed volumes of human dental enamel.

Fig. 2 The arrangements of metal core and ligands.

Fig. 6 SWD in the three seismically active areas shown in Fig. 3.

Fig. 1 Demographic shifts in knowledge producers.

Fig. 2 Quantification and mechanisms leading to the CAH for reentrant and doubly reentrant geometries at zero applied pressure. Quantification and mechanisms.

Fig. 4 Reentrant and doubly reentrant transition state analysis.

Fig. 1 Comparison of experimental and simulated NMR relaxation rates at 278 to 298 K. Comparison of experimental and simulated NMR relaxation rates at.

Fig. 6 Comparison of properties of water models.

Fig. 3 Faculty placement distributions.

Fig. 3 ACID isosurfaces of the model complex 2′ separated into the π- and σ-contribution. ACID isosurfaces of the model complex 2′ separated into the π-

Fig. 2 Fluence-dependent emission characteristics of CH3NH3PbI3 recorded at 15 and 300 K. Fluence-dependent emission characteristics of CH3NH3PbI3 recorded.

Fig. 1 Cryo-EM structure of yeast Elp123 showing its active site.

Fig. 5 Structural photocycle for DmCry.

Fig. 3 Controlled phase shift.

Fig. 3 Forward model. Forward model. Summary of the resampled Monte Carlo simulations shown as histograms for epoch 1 (red), epoch 2 (green), and epoch.

Effects of a human FABP7 point mutation on FABP7 protein structure

Fig. 1 Map of the study area including the northwestern end of the Hawaiian Ridge and the southern portion of the ESC. Map of the study area including.

Electronic structure of the oligomer (n = 8) at the UB3LYP/6-31G

Fig. 4 Identification of C

Fig. 1 Data collection at a 40° tilt angle enabled reconstruction of a cryo-EM map of the NRTN-GFRα2-RET complex at a 5.7-Å resolution. Data collection.

Fig. 3 Transport characterization of dry-assembled devices.

Fig. 4 Experimental outputs.

Fig. 3 Evolutions of freshwater transport and salinity.

Fig. 4 Identification of miRNA packaged within MBVs.

Fig. 2 Large-area and high-density assembly of AuNPs.

Fig. 3 C9ORF72 interacts with SMCR8 in a DENN domain–dependent manner.

Fig. 2 Results of the learning and testing phases.

Fig. 4 Randomized benchmarking measurement.

Fig. 1 Empirical probability density functions of the estimated climatic drivers. Empirical probability density functions of the estimated climatic drivers.

Fig. 3 CFD simulations. CFD simulations. (A to R) Details of water flow around Tribrachidium oriented at 0° to the current. Model with original height.

Fig. 4 Relationships between light and economic parameters.

Fig. 2 Stabilizing the lithium-electrolyte interface.

Fig. 3 Plumage brightness (PC1) for each sex in relation to morphological, ecological, and behavioral traits. Plumage brightness (PC1) for each sex in.

Overall structure of AxqNOR and interhelical dimer interactions

Fig. 7 Global change in the collective mass for wild mammals, humans, cattle, and all livestock for the years 1900–2050. Global change in the collective.

Fig. 3 Plastic ingestion and DMS responsiveness among procellariiform seabirds. Plastic ingestion and DMS responsiveness among procellariiform seabirds.

Dcr-2 directly interacts with Toll 3′UTR via its PAZ domain in vitro

Fig. 1 Fractional coverage of the mapping method used in this study.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Fig. 2 Comparison of Bayesian estimates of the TMRCA of the Native American founder haplogroups and of the divergence from Siberian lineages. Comparison.

Fig. 1 The s-s/w-w H-bond pairing principle and the effect of protein-ligand H-bonds on protein-ligand binding. The s-s/w-w H-bond pairing principle and.

Fig. 5 Potential-energy energy profiles of 1-HAQ.

Fig. 2 XRD spectra and molecular structures of tetragonal and monoclinic crystal phase KDP samples. XRD spectra and molecular structures of tetragonal.

Fig. 2 Number of years that would have been required for the observed vertebrate species extinctions in the last 114 years to occur under a background.

Fig. 19 Comparisons between sky brightness NPS CCD observations and atlas predictions. Comparisons between sky brightness NPS CCD observations and atlas.

Fig. 5 Fabrication of origami structures by two-side illuminations.

Fig. 2 Inferring the diffusion equation from a single Brownian motion.

Fig. 3 Efficiency of the GDML predictor versus a model that has been trained on energies. Efficiency of the GDML predictor versus a model that has been.

Fig. 5 Frequency of appearances of immigrant vertebrate taxa or their oldest known descendants in opposing continents as observed in well-dated fossiliferous.

Fig. 5 Density plots showing the relationship between growth responses to extreme events and site-level mean precipitation from all sites (N = 1314). Density.

Fig. 2 Growth kinetics of borophene on silver.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

Fig. 4 Reconstruction of the nematocysts in Nematodinium sp.

Fig. 4 Scaling laws distinguish biochemical networks from random networks across levels of organization. Scaling laws distinguish biochemical networks.

Fig. 3 Voltage-driven phase switching in a 1T-TaS2 nano-thick crystal.

Fig. 4 Relationship of plastic ingestion and nesting behavior.

Fig. 2 Daily TNC pickups and drop-offs for an average Wednesday in fall 2016 (1). Daily TNC pickups and drop-offs for an average Wednesday in fall 2016.

Fig. 4 MxB intermolecular assembly interfaces and their role in the MxB assembly and HIV-1 inhibition. MxB intermolecular assembly interfaces and their.

Fig. 1 Uplift of the Isthmus of Panama and global sea levels over the last 20 My. Uplift of the Isthmus of Panama and global sea levels over the last 20.

Fig. 3 Spatial distribution of the shoot density (high densities are represented in dark green and low ones in bright yellow) in a simulation of a P. oceanica.

Fig. 2 Time series of secularization versus GDP per capita, from four illustrative countries, over the 20th century. Time series of secularization versus.

Presentation transcript:

Fig. 2 Views of the Pincer-FATKIN interface and the dimer interface. Views of the Pincer-FATKIN interface and the dimer interface. (A) A closeup view of the Pincer domains and their interactions with the FATKIN. (B) The bipartite interface between the two protomers in the closed dimer. The upper interface includes portions of the kinase domain and TRD3. (C) The lower interface, primarily including TRD2 and a portion of TRD3, shown as ribbons with the density of the closed dimer interface (purple and blue). Domagoj Baretić et al. Sci Adv 2017;3:e1700933 Copyright © 2017, The Authors