Fig. 3. Cell-autonomous loss of GABAergic interneurons in the OB of newborn and adult conditional GFRα1 mutants. Cell-autonomous loss of GABAergic interneurons.

Slides:

Advertisements

Similar presentations

Volume 30, Issue 6, Pages (September 2014)

Advertisements

Scanning electron microscopy analysis of EGK-I to -V chick embryos.

Volume 21, Issue 6, Pages (December 1998)

Fig. 5. Prip silencing enhances the co-localization of GABARAP with insulin vesicles and β-tubulin.Co-localization of GABARAP (green) with insulin (red)

Fig. 1. Overview of the nervous system of the adult S. roscoffensis.

Fig. 8. In vitro effect of CMPs on adult DSS-treated stomach explants.

Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 5. Differentiated cells sort to the outer layer, regardless of E- or N-cadherin status.Wildtype and mutant ES cells were distinguished by GFP expression.

Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.

Fig. 4. Seeding density modulates cell shape in both cell types

Fig. 2. Proportion of motile objects and track length

Fig. 2. abu/pqn genes are expressed in the pharyngeal cuticle

Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.

Fig. 10. Ratiometric live imaging of di-4-ANEPPDHQ in growing pollen tubes.(A) Higher and lower membrane order distribution in control and BCD treated.

Expression of Shh-Gli target genes in astrocyte progenitors.

Fig. 7. Knockdown of Meis1 abolishes CR4. 2-GFP expression

Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.

Fig. 5. Onecut transcription factors are important for the correct generation of the mdDA neuronal population.(A) Schematic representation of the region.

Fig. 1. Loss of PC following INT depletion

Fig. 2. Transfection and clonal selection of rat pluripotent stem cells to generate stable transgenic lines. Transfection and clonal selection of rat pluripotent.

Fig. 4. The model of malate metabolism in fruit cells under different K level conditions. The model of malate metabolism in fruit cells under different.

Ectopic sprouting and proliferation in Rbpj veins.

Fig. 1. Pigmentation and melanophore counts of rainbow trout parr and smolt caudal fins.Pigmentation of (A) parr and (B) smolt. Pigmentation and melanophore.

eb1a-2 eb1b-3 double-mutant plants display skewed and shorter roots

Fig. 2. DDR1 over-expression enhances collagen fibril reorganization

Fig. 3. Mutation of Y520 and Y667 result in increased delivery of prestin to the apical surface of MDCK cells.MDCK cells transiently transfected with wt.

Fig. 8. Knockdown of Meis1 reduces the expression of Foxn4 and Lim1+2

Fig. 3. Characterization of unclassified cells (UCs).

Fig. 4. Detection of dFMR1 mRNA in dFMRP granules by FISH

Fig. 7. VCBP-C and chitin localization in stomach sections of adult DSS- and CMP-treated animals. VCBP-C and chitin localization in stomach sections of.

Fig. 4. Non-autonomous rescue of puc expression in DME cells

Fig. 5. Differentiated cells sort to the outer layer, regardless of E- or N-cadherin status.Wildtype and mutant ES cells were distinguished by GFP expression.

Fig. 6. Comparison of Plk4 with Sas-6 localization

Fig. 7. Lhx1-RNAi reduces the eye size

Fig. 7. Representative images of control (Cas9+GFP) and Cas9+gRNA+GFP co-injected embryos on day 4 of culture, showing nuclear-imported GFP (green) and.

Loss of serotonergic markers after Smed-pitx RNAi is not due to stem cell-based turnover. Loss of serotonergic markers after Smed-pitx RNAi is not due.

Fig. 6. STK35 KO mice show ovary defects.

Fig. 2. Fluorescent images indicating the cytoskeleton of human bone marrow-derived mesenchymal stem cells (hBMSCs) subjected to cyclic stretching. Fluorescent.

Fig. 6. Apical polarity of primitive endoderm cells on surface of embryoid bodies.Embryoid bodies were analyzed by immunofluorescence microscopy for GATA4.

Fig. 2. mip120 null mutants have abnormal egg chamber development.

The idefix phenotype first becomes visible during metamorphosis

Reb does not play a significant role in regulating TGF-β signaling

Fig. 6. Meis1 protein is present in CR4. 2-GFP+ and Foxn4+ cells

Fig. 2. Immunostaining for ClC-5 in isolated hog gastric mucosa

Fig. 1. Loss of PC following INT depletion

Fig. 9. Loss of the cholinergic receptor subunit Chrna6 does not alter the development and organization of the mdDA system.(A) In situ hybridization experiments.

Fig. 3. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice.

Deletion of Sox2 in adult mice inhibits incisor regeneration.

Fig. 8. Tracking details and coordinate systems.

Fig. 2. iPSCs produce functional osteoblasts.

Ibm1 and edm2 mutants generate more stomatal divisions in the leaf epidermis. ibm1 and edm2 mutants generate more stomatal divisions in the leaf epidermis.

Fig. 3. transparent is required cell-autonomously in iridophores

Fig. 2. Expression of Cx43 mutant T154A resulted in non-radial spreading and formation of protrusions in J558µm3 cells spreading in response to BCR signaling.(A)

Fig. 4. CR4.2 may be active in amacrine cells but not in ganglion cells.Chick retinas were electroporated with either the control CAG-GFP construct or.

Peroxisome speeds were slower in patient and control cells.

Fig. 2. Acetylation stiffens primary cilia.

Fig. 6. RhoB is required for Rnd3-induced stress fibre formation

Fig. 5. Upregulation and subcellular relocalization of Hsp70 in striated muscles overexpressing either DVAP-V260I or DVAP-WT constructs.(A) NMJs of BG57-Gal4/+

Fig. 7. Eye defects in STK35 KO mouse.

Fig. 3. Mean force and velocity during jumping

Fig. 5. EGL-20 inhibits anterior and posterior orientation of UNC-40 asymmetric localization and the formation of axons from these sites.(A–D) HSN neurons.

mip120 null egg chambers have a condensed nurse cell DNA phenotype

Fig. 5. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated.

Fig. 5. Behaviours of the wild-types Oregon-R at two temperatures.

Fig. 1. lgl interacts genetically with Argonaute 1 (AGO1) in the eye.

Fig. 7. Analysis of dFMRP kinetics in dFMRP granules by FRAP

Co-expression of periostin and Sox10 in DRG and DRG explant cultures.

PC loss in Nhe6-null mouse cerebellum, female and male.

Presentation transcript:

Fig. 3. Cell-autonomous loss of GABAergic interneurons in the OB of newborn and adult conditional GFRα1 mutants. Cell-autonomous loss of GABAergic interneurons in the OB of newborn and adult conditional GFRα1 mutants. (A) Representative images of the OB of newborn Gad67Cre;R1CGfx/fx conditional mutant and R1CGfx/fx control mice immunostained for markers of OB GABAergic interneurons: tyrosine hydroxylase (TH), Calbindin and Calretinin. Scale bar: 100 µm. (B) Representative images of the OB of P56 Gad67Cre;R1CGfx/fx conditional mutant and R1CGfx/fx control mice along the medial surface immunostained for markers of OB GABAergic interneurons: tyrosine hydroxylase (TH), Calbindin and Calretinin. Scale bar: 100 µm. (C) Quantification of the number of cells expressing TH, Calbindin (CB) and Calretinin (CR) in the OB of newborn Gad67Cre;R1CGfx/fx conditional mutants and R1CGfx/fx control mice. The values represent total number of cells in fields encompassing the entire OB. N=6 mice per group; *P<0.05; ***P<0.0005. (D) Quantification of the number of cells expressing TH, Calbindin (CB) and Calretinin (CR) in the OB of P56 Gad67Cre;R1CGfx/fx conditional mutants and R1CGfx/fx control mice. The values represent number of cells counted in the glomerular layer of the medial surface of the OB (see the Materials and Methods for details). N=6 mice per group; **P<0.005; ***P<0.0005. ONL, olfactory nerve layer; GL, glomerular layer; EPL, external plexiform layer; MI, mitral cell layer; GR, granule cell layer. Sabrina Zechel et al. Biology Open 2018;7:bio033753 © 2018. Published by The Company of Biologists Ltd