Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development  Summer B. Thyme, Alexander F. Schier 

Slides:



Advertisements
Similar presentations
Genome Engineering with CRISPR-Cas9 in the Mosquito Aedes aegypti
Advertisements

Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors Liang Yang, Yong Qi, Yunlei Yang Cell Reports Volume 11, Issue.
Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics Matthias Farlik, Nathan C. Sheffield, Angelo Nuzzo,
Irreplaceability of Neuronal Ensembles after Memory Allocation Naoki Matsuo Cell Reports Volume 11, Issue 3, Pages (April 2015) DOI: /j.celrep
Mitotic Spindle Asymmetry: A Wnt/PCP-Regulated Mechanism Generating Asymmetrical Division in Cortical Precursors Delphine Delaunay, Véronique Cortay, Dorothée.
Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr
Consecutive Positive Feedback Loops Create a Bistable Switch that Controls Preadipocyte-to-Adipocyte Conversion Byung Ouk Park, Robert Ahrends, Mary N.
Charting Monosynaptic Connectivity Maps by Two-Color Light-Sheet Fluorescence Microscopy Christian J. Niedworok, Inna Schwarz, Julia Ledderose, Günter.
A Dynamic Microtubule Cytoskeleton Directs Medial Actomyosin Function during Tube Formation Alexander J.R. Booth, Guy B. Blanchard, Richard J. Adams, Katja.
Human Embryonic and Induced Pluripotent Stem Cell Research Trends: Complementation and Diversification of the Field Sabine Kobold, Anke Guhr, Andreas Kurtz,
Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease Roshni Srivastava, Jiasheng Zhang, Gwang-woong.
Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway Gil Ju Seo, Aerin Yang, Brandon Tan, Sungyoon Kim, Qiming Liang, Younho Choi, Weiming Yuan,
The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.
Nucleotide Pool Depletion Induces G-Quadruplex-Dependent Perturbation of Gene Expression Charikleia Papadopoulou, Guillaume Guilbaud, Davide Schiavone,
Noncanonical Genomic Imprinting Effects in Offspring Paul J. Bonthuis, Wei-Chao Huang, Cornelia N. Stacher Hörndli, Elliott Ferris, Tong Cheng, Christopher.
Ensemble Force Changes that Result from Human Cardiac Myosin Mutations and a Small-Molecule Effector Tural Aksel, Elizabeth Choe Yu, Shirley Sutton, Kathleen.
Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation Mohan Malleshaiah, Megha Padi, Pau Rué, John Quackenbush,
MiR-137 Modulates a Tumor Suppressor Network-Inducing Senescence in Pancreatic Cancer Cells Mathieu Neault, Frédérick A. Mallette, Stéphane Richard Cell.
Genomic Regions Flanking E-Box Binding Sites Influence DNA Binding Specificity of bHLH Transcription Factors through DNA Shape Raluca Gordân, Ning Shen,
ABH2 Couples Regulation of Ribosomal DNA Transcription with DNA Alkylation Repair Pishun Li, Shuman Gao, Lina Wang, Fang Yu, Jialun Li, Chuangui Wang,
2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.
Oscillatory Activity in Developing Prefrontal Networks Results from Theta-Gamma- Modulated Synaptic Inputs Sebastian H. Bitzenhofer, Kay Sieben, Kai D.
DNA Entry into and Exit out of the Cohesin Ring by an Interlocking Gate Mechanism Yasuto Murayama, Frank Uhlmann Cell Volume 163, Issue 7, Pages
Expanding the Biologist’s Toolkit with CRISPR-Cas9
Genome-editing Technologies for Gene and Cell Therapy
DNA Replication Reaches the Breaking Point
Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus  Li Zhou, Ming-Zhe Liu, Qing.
162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo
Volume 1, Issue 6, Pages (December 2013)
Condensin and Hmo1 Mediate a Starvation-Induced Transcriptional Position Effect within the Ribosomal DNA Array  Danni Wang, Andres Mansisidor, Gayathri.
Skill Development in Graduate Education
In This Issue Cell Volume 158, Issue 5, (August 2014)
DNA Polymerases at the Replication Fork in Eukaryotes
Volume 18, Issue 9, Pages (February 2017)
Volume 13, Issue 7, Pages (November 2015)
CRISPR-Cas9 for in vivo Gene Therapy: Promise and Hurdles
CRISPR genome-editing: A medical revolution
Volume 152, Issue 1, (January 2013)
ATM Creates a Veil of Transcriptional Silence
Current Progress in Therapeutic Gene Editing for Monogenic Diseases
Do DNA Double-Strand Breaks Drive Aging?
Volume 130, Issue 6, (September 2007)
Genome-editing Technologies for Gene and Cell Therapy
Need for Speed: Mechanical Regulation of a Replicative Helicase
Jean Cadet, Thierry Douki  Journal of Investigative Dermatology 
Aging: A Sirtuin Shake-Up?
DNA Double-Strand Breaks Come into Focus
Breaking News on Fragile Sites in Cancer
CRISPR-Mediated Base Editing without DNA Double-Strand Breaks
Volume 143, Issue 6, (December 2010)
Translocation Mapping Exposes the Risky Lifestyle of B Cells
Golgi Feels DNA’s Pain Cell
Rapid Automatic Motor Encoding of Competing Reach Options
Volume 15, Issue 1, Pages (April 2016)
Andrew R. Bassett, Charlotte Tibbit, Chris P. Ponting, Ji-Long Liu 
Table of contents The Journal for Nurse Practitioners
Condensin and Hmo1 Mediate a Starvation-Induced Transcriptional Position Effect within the Ribosomal DNA Array  Danni Wang, Andres Mansisidor, Gayathri.
740. Prevention of Radiation-Induced Lung Injury by Administration of Gene-Modified Mesenchymal Stem Cells    Molecular Therapy  Volume 20, Pages S285-S286.
At Loose Ends: Resecting a Double-Strand Break
Volume 71, Issue 9, Pages (May 2007)
Are Mouse Telomeres Going to Pot?
Volume 163, Issue 4, (November 2015)
Volume 163, Issue 2, (October 2015)
Stem Cells Matter in Response to Fasting
Macrophage Metabolism Shapes Angiogenesis in Tumors
Axis Formation: Squint Comes into Focus
Volume 11, Issue 7, Pages (May 2015)
Volume 134, Issue 6, (September 2008)
In This Issue Cell Volume 145, Issue 3, (April 2011)
Volume 148, Issue 1, (January 2012)
Presentation transcript:

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development  Summer B. Thyme, Alexander F. Schier  Cell Reports  Volume 15, Issue 7, Pages 1611-1613 (May 2016) DOI: 10.1016/j.celrep.2016.04.089 Copyright © 2016 The Author(s) Terms and Conditions

Figure 1 Polq Is Required for Survival following Cas9-Induced DNA DSBs (corrected) Cell Reports 2016 15, 1611-1613DOI: (10.1016/j.celrep.2016.04.089) Copyright © 2016 The Author(s) Terms and Conditions

Figure 1 Polq Is Required for Survival following Cas9-Induced DNA DSBs (original) Cell Reports 2016 15, 1611-1613DOI: (10.1016/j.celrep.2016.04.089) Copyright © 2016 The Author(s) Terms and Conditions