Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: a prospective randomized.

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Presentation transcript:

Effect of the insulin sensitizers metformin and pioglitazone on endothelial function in young women with polycystic ovary syndrome: a prospective randomized study Katerina K. Naka, M.D., Ph.D., Sophia N. Kalantaridou, M.D., Maria Kravariti, M.D., Aris Bechlioulis, M.D., Nikolaos Kazakos, M.D., Karim A. Calis, Pharm.D., M.P.H., Antonis Makrigiannakis, M.D., Ph.D., Christos S. Katsouras, M.D., George P. Chrousos, M.D., Agathocles Tsatsoulis, M.D., Ph.D., Lampros K. Michalis, M.D. Fertility and Sterility Volume 95, Issue 1, Pages 203-209 (January 2011) DOI: 10.1016/j.fertnstert.2010.06.058 Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Flow-mediated dilation (FMD) in the control women and in the three groups of women with PCOS at baseline and at 6-month follow-up. ∗P<.001 versus controls. †P<.001 versus baseline in metformin group. ‡P<.001 versus baseline in pioglitazone group. Fertility and Sterility 2011 95, 203-209DOI: (10.1016/j.fertnstert.2010.06.058) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions