Deferoxamine-related fatal nasal–orbital–cerebral mucormycosis

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Deferoxamine-related fatal nasal–orbital–cerebral mucormycosis V.-C. Wu, R. Wang, T.-S. Lai, K.-D. Wu  Kidney International  Volume 70, Issue 11, (December 2006) DOI: 10.1038/sj.ki.5001736 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Photograph of the patient, showing swelling and erythematous skin lesions on the left forehead and periorbital areas and two nodules measuring 3 × 1 cm and 2 × 1 cm on the nasal ridge, with local tenderness and fragile bony structure on palpation. Kidney International 2006 70, DOI: (10.1038/sj.ki.5001736) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 2 Gadolinium-enhanced T1-weighted magnetic resonance brain imaging.(a) Mucormycosis with invasion into the paranasal sinus; the mucosa of the left maxillary sinus was thickening, and bone destruction of the nasal bone, hard palate, and paranasal sinuses was observed (arrow). (b) Extension of mucous debris to the nasal cartilage, nasal floor, and hard palate (arrow). Kidney International 2006 70, DOI: (10.1038/sj.ki.5001736) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 3 Mucormycosis was identified from the pus culture (arrows). (Hematoxylin and eosin stain; original magnification, ×200.)1818 Kidney International 2006 70, DOI: (10.1038/sj.ki.5001736) Copyright © 2006 International Society of Nephrology Terms and Conditions