Aneurysmal and occlusive atherosclerosis of the human abdominal aorta

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Aneurysmal and occlusive atherosclerosis of the human abdominal aorta Chengpei Xu, MD, PhDa, Christopher K. Zarins, MDa, Seymour Glagov, MDb Journal of Vascular Surgery Volume 33, Issue 1, Pages 91-96 (January 2001) DOI: 10.1067/mva.2001.109744 Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 1 Standardized specimen sampling: transverse aortic rings were sectioned from the supraceliac aorta 2 cm proximal to the celiac artery (level T, thoracic aorta) and from five standard locations in the infrarenal aorta. Level 1 is the juxtarenal segment 1 cm distal to the renal arteries; level 5 is the segment 1 cm proximal to the iliac bifurcation. Level 3 is midway between levels 1 and 5. Level 2 is the segment at the midpoint between levels 1 and 3, and level 4 is the midpoint between levels 3 and 5. Journal of Vascular Surgery 2001 33, 91-96DOI: (10.1067/mva.2001.109744) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 2 Representative correlations between the IELA and plaque area and between the IELA and age shown in panels A and B, respectively, for level 3 section. The IELA was used to represent the aortic size. IELA, Internal elastic lamina area. Journal of Vascular Surgery 2001 33, 91-96DOI: (10.1067/mva.2001.109744) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 3 Abdominal aorta with well built-up plaque (P ) and relatively normal media (M ). The elastic lamellae in the media are stained dark (Weigert-van Geison staining). The arrows indicate the inner margin of the media. The remodeling phenomena are apparent in the bottom part of the intimal plaque with newly formed elastic lamellae. Journal of Vascular Surgery 2001 33, 91-96DOI: (10.1067/mva.2001.109744) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions

Fig. 4 Abdominal aorta with large plaque (P ) and diminishing thickness of the media (M ). The internal elastic lamellae (IEL) has mostly disappeared, and the inner part of the media has been eroding (arrows ). There is little remodeling evidence in the intimal plaque (Weigert-van Geison staining). Journal of Vascular Surgery 2001 33, 91-96DOI: (10.1067/mva.2001.109744) Copyright © 2001 Society for Vascular Surgery and The American Association for Vascular Surgery Terms and Conditions