Severe Necrotic Reaction to 23-Valent Polysaccharide Pneumococcal Vaccine in a Patient with STAT3 Deficiency Mervin Piñones, MD, Cecilia Vizcaya, MD,

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Presentation transcript:

Severe Necrotic Reaction to 23-Valent Polysaccharide Pneumococcal Vaccine in a Patient with STAT3 Deficiency Mervin Piñones, MD, Cecilia Vizcaya, MD, Guillermo Pérez-Mateluna, BS, Rodrigo Hoyos-Bachiloglu, MD, MMSc, Arturo Borzutzky, MD The Journal of Allergy and Clinical Immunology: In Practice Volume 7, Issue 5, Pages 1631-1632 (May 2019) DOI: 10.1016/j.jaip.2019.01.033 Copyright © 2019 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Progression of local adverse reaction to the PPSV23 at injection site. A, Erythema at day 1. B, Blisters confluent to become a large bulla. C, Necrotic ulcer. D, Ulcer after surgical debridement. E, Lesion after skin graft. F, Scar after 6-month follow-up. The Journal of Allergy and Clinical Immunology: In Practice 2019 7, 1631-1632DOI: (10.1016/j.jaip.2019.01.033) Copyright © 2019 American Academy of Allergy, Asthma & Immunology Terms and Conditions