Incidence and progression of mild aortic regurgitation after Tirone David reimplantation valve-sparing aortic root replacement  Elizabeth H. Stephens,

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Incidence and progression of mild aortic regurgitation after Tirone David reimplantation valve-sparing aortic root replacement  Elizabeth H. Stephens, MD, PhD, David H. Liang, MD, PhD, John-Peder Escobar Kvitting, MD, PhD, Fabian A. Kari, MD, Michael P. Fischbein, MD, PhD, R. Scott Mitchell, MD, D. Craig Miller, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 147, Issue 1, Pages 169-178.e3 (January 2014) DOI: 10.1016/j.jtcvs.2013.09.009 Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 AR grade on preoperative and postoperative (1 year and most recent) TTE for all patients in the “mild early AR” subgroup (n = 41). Daughter graphs demonstrate the corresponding data for “mild stable AR” (n = 35) and “progression of mild AR” (n = 6) subsets. AR, Aortic regurgitation; TTE, transthoracic echocardiogram. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 169-178.e3DOI: (10.1016/j.jtcvs.2013.09.009) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 A, Log-rank (Mantel–Cox) analysis of progression of AR in patients with mild AR on the 1-year TTE. Error bars indicate standard error of the estimate. Number of patients at risk in each group is listed under the x-axis. Note the relatively few number of patients at risk (n = 14) at 60 months. On log-rank analysis, aortic valve repair versus no repair has a P value of .006. All patients, except 1 with AR that progressed to moderate, remained stable at the time of the latest follow-up echocardiogram. B, Log-rank (Mantel–Cox) analysis of progression of AR in patients with mild AR on the 1-year TTE. Error bars indicate standard error of the estimate. Number of patients at risk in each group is listed under the x-axis. Note the relatively few number of patients at risk (14) at 60 months. On log-rank analysis, preoperative AR grade had a P value of .003. All patients, except 1 with AR that progressed to moderate, remained stable through the latest follow-up. The red labels on the severe preoperative AR curves indicate the most recent AR grade for the patients in whom AR progressed. The patient with 4+ AR ultimately underwent reoperation. AR, Aortic regurgitation; AV, atrioventricular. The Journal of Thoracic and Cardiovascular Surgery 2014 147, 169-178.e3DOI: (10.1016/j.jtcvs.2013.09.009) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions