Bone metaplasia associated with chronic allograft nephropathy

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Bone metaplasia associated with chronic allograft nephropathy K. Tousignant, V. Phan, M.J. Clermont, K. Metellus, G. Perreault, H. Sartelet  Kidney International  Volume 70, Issue 3, (August 2006) DOI: 10.1038/sj.ki.5001678 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Renal allograft biopsy. (a) Histological features of renal cortex with two glomeruli surrounded by a lymphocytic interstitial infiltrate associated with acute cellular rejection. The usual morphology of the cortex is disrupted by multiple zones of bone metaplasia, which consist of osseous matrix, osteocytes, and osteoblasts hematoxylin–phloxin–safran; original magnification, ×200.) (b) Cross section of an interlobular artery, showing an intimal fibrous narrowing compatible with chronic allograft nephropathy. (hematoxylin–phloxin–safran; original magnification, ×100.) Kidney International 2006 70, DOI: (10.1038/sj.ki.5001678) Copyright © 2006 International Society of Nephrology Terms and Conditions