The functional genotype of glutathione S-transferase T1 gene is strongly associated with increased risk of idiopathic infertility in Russian men Alexey.

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Presentation transcript:

The functional genotype of glutathione S-transferase T1 gene is strongly associated with increased risk of idiopathic infertility in Russian men Alexey V. Polonikov, M.D., Sergey L. Yarosh, M.D., Elena V. Kokhtenko, Ph.D., Nina I. Starodubova, M.D., Sergey P. Pakhomov, M.D., Valentina S. Orlova, M.D. Fertility and Sterility Volume 94, Issue 3, Pages 1144-1147 (August 2010) DOI: 10.1016/j.fertnstert.2009.11.006 Copyright © 2010 Terms and Conditions

Figure 1 Electrophoretic pattern of GSTM1 and GSTT1 null polymorphisms (multiplex polymerase chain reaction method developed by Abdel-Rahman et al. [11]). Band sizes are indicated on the left of gel. Band size 480 bp is GSTT1 expressor genotype. Band size 350 bp is β-globin gene (coamplified internal control). Band size 215 bp is GSTM1 expressor genotype. Lanes 1, 2, 4, 6, 7, and 11: GSTT1 expressor/GSTM1 expressor genotype. Lanes 3, 5, 8, 9, and 10, GSTT1 expressor/GSTM1 null genotype. Lane 12, GSTT1 null/GSTM1 null genotype. Fertility and Sterility 2010 94, 1144-1147DOI: (10.1016/j.fertnstert.2009.11.006) Copyright © 2010 Terms and Conditions