Volume 69, Issue 10, Pages (May 2006)

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Volume 69, Issue 10, Pages 1858-1864 (May 2006) The influence of CYP3A gene polymorphisms on cyclosporine dose requirement in renal allograft recipients H.-S. Eng, Z. Mohamed, R. Calne, C.C. Lang, M.A. Mohd, W.-T. Seet, S.-Y. Tan Kidney International Volume 69, Issue 10, Pages 1858-1864 (May 2006) DOI: 10.1038/sj.ki.5000325 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Cyclosporine dose requirements in relation to CYP3A5 and CYP3AP1 linked genotypes at months 1, 3, and 6 post-transplantation in 67 renal allograft recipients. (a) All Patients, significant differences in CsA dose requirement were observed between patients with *1*1*1*1 and patients with *1*3*1*3 or *3*3*3*3. (b) Chinese Patients, when Chinese patients were analyzed separately, the difference in CsA dose requirement persists at month 6 (P>0.05). Kidney International 2006 69, 1858-1864DOI: (10.1038/sj.ki.5000325) Copyright © 2006 International Society of Nephrology Terms and Conditions