Chyluria presenting as milky urine and nephrotic-range proteinuria

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Chyluria presenting as milky urine and nephrotic-range proteinuria J.-T. Cheng, S. Mohan, S.H. Nasr, V.D. D'Agati  Kidney International  Volume 70, Issue 8, Pages 1518-1522 (October 2006) DOI: 10.1038/sj.ki.5001703 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Thin smear of urine sediment stained with modified Wright stain (Hansel's stain) showing lymphocytes and isomorphic erythrocytes (original magnification × 400). Kidney International 2006 70, 1518-1522DOI: (10.1038/sj.ki.5001703) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 2 Chloroform extraction of fat globules from chyluria. (a) To an aliquot of milky urine, an equal volume of chloroform is added. (b) Result of mixing and agitation of the mixture. (c) After centrifugation of the agitated mixture, there is clearing of milky urine with extraction of fat globules in the chloroform layer (bottom). (d) Chloroform extraction after the addition of Sudan III to the milky urine. Note the appearance of red-stained fat globules in the bottom chloroform layer and clearing of the milky urine. Kidney International 2006 70, 1518-1522DOI: (10.1038/sj.ki.5001703) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 3 A representative electron micrograph shows normal glomerular basement membrane thickness with intact foot processes and absence of electron dense deposits (original magnification × 2000). Kidney International 2006 70, 1518-1522DOI: (10.1038/sj.ki.5001703) Copyright © 2006 International Society of Nephrology Terms and Conditions