Figure 2 Neuroimaging characteristics of TARDBP carriers Neuroimaging characteristics of TARDBP carriers Brain 99mTc-ethylcysteinate dimer-SPECT, FDG-PET, and MRI of 6 patients: F242-001 (A), F575-001 (B), F242-002 (C and E), F389-014 (D), FAPP007-001 (F and H), and M008015-001 (G). Note the hypoperfusion and hypometabolism of the temporal pole in the 3 patients F575-001, F389-014, and FAPP007-001 presenting with semantic dementia. Paola Caroppo et al. Neurol Genet 2016;2:e80 © 2016 American Academy of Neurology