Lecture 7c 25 October 2010

ADEK   ABSORPTION AND TRANSPORT CARRIERS FOR BOTH LIPOPROTEINS IN THE BLOOD

FUNCTIONAL FOODS VARIOUSLY RICH IN A RANGE OF VITAMINS BUT HAVE NOT BEEN SHOWN TO BE AS EFFECTIVE AS SUPPLEMENTS THEMSELVES WHY? CONCENTRATION/ISOLATION AND POSSIBLE INTERFERENCE FACTORS

VITAMINS AS NUTRACEUTICALS   SUPPLEMENTATION ONLY IF DIET DOES NOT SUPPLY ENOUGH OR HAVE SECONDARY NUTRIENT DEFICIENCIES THAT DIET WILL NOT OVERCOME E.G. -VITAMIN K ELDERLY-LOW DIETARY INTAKE OF VITAMIN K- GREEN LEAFY VEGGIES DEFICIT ELDERLY-ANTIBIOTIC THERAPY OFTEN DEPLETES VITAMIN K PRODUCING BACTERIA

VITAMINS AS NUTRACEUTICALS CONTINUED   REQUIRED IF SUPPLEMENTS APPARENTLY HELP WITH A PARTICULAR DISEASE HOWEVER!-TOXICITY- ESPECIALLY WITH FAT SOLUBLE VITAMINS

VITAMINS AS NUTRACEUTICALS CONTINUED HEART DISEASE   BETA-CAROTENE, VITAMIN E ARE ANTIOXIDANTS LDL’S CONTENT OF BETA-CAROTENE AND VITAMIN E DICTATE OXIDATION OF LDL VITAMIN E- HIGH (NON-TOXIC) DOSES GIVE DECREASED PLATELET FUNCTION

VITAMINS AS NUTRACEUTICALS CONTINUED DIABETES   BETA-CAROTENE, VITAMIN E ARE DEPLETED IN DIABETES AND THIS IS BELIEVED TO ENHANCE LOW DENSITY LIPOPROTEIN OXIDATION WHICH ENCOURAGES ATHEROSCLEROSIS

VITAMINS AS NUTRACEUTICALS CONTINUED CANCER   OXIDATION OF E.G. DNA CONTRIBUTES TO CANCER AND BETA-CAROTENE, VITAMIN E COMBATS THIS OXIDATION

VITAMINS AS NUTRACEUTICALS CONTINUED OSTEOPOROSIS   VITAMIN D AND CALCIUM SUPPLEMENTS OFTEN GIVEN TO ELDERLY TO OVERCOME HORMONALLY INDUCED BONE LOSS

VITAMINS AS NUTRACEUTICALS CONTINUED COELIAC DISEASE   IRRITATION OF SMALL INTESTINE WITH GLUTEN (A PROTEIN PART OF SOME GRAINS) –IMMUNE RESPONSE-INFLAMMATION-MALABSORPTION SOLUTIONS A)ELIMINATE –WHEAT, OATS, BARLEY AND RYE ALL OF WHICH CONTAIN GLUTEN B) ADEK- SUPPLEMENT UNTIL HEAL (VIA GLUTEN FREE AND/OR DRUGS)

VITAMIN A-IMPORTANT FOR SKIN AND IMMUNE FUNCTION VITAMINS AS NUTRACEUTICALS CONTINUED BURN PATIENTS   REGULAR DIET A PROBLEM VITAMIN A-IMPORTANT FOR SKIN AND IMMUNE FUNCTION

ANTIOXIDANT –BETA CAROTENE AND VITAMIN E HYPOTHESIZED TO COMBAT VITAMINS AS NUTRACEUTICALS CONTINUED SMOKERS   ANTIOXIDANT –BETA CAROTENE AND VITAMIN E HYPOTHESIZED TO COMBAT OXIDISATION AGENTS FOUND IN SMOKE

VITAMINS BETA-CAROTENE AND E IF NOT SUFFICIENT IN DIET- VITAMINS AS NUTRACEUTICALS CONTINUED PULMONARY DISEASE   VITAMINS BETA-CAROTENE AND E IF NOT SUFFICIENT IN DIET- ANTIOXIDANT ROLE

VITAMINS AS NUTRACEUTICALS CONTINUED CYSTIC FIBROSIS   FAT SOLUBLE VITAMINS INADEQUATELY ABSORBED VITAMIN ADEK SUPPLEMENTATION VIA INTRAVENOUS IF NECESSARY (PANCREATIC FUNCTION IS NOT ABLE TO WORK IN THIS DISEASE)

WHAT IS NEW IN FAT SOLUBLE VITAMIN RESEARCH ? VITAMIN D INTAKE MAY REDUCE BREAST CANCER RISK