Chemokines and their receptors in allergic disease

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Presentation transcript:

Chemokines and their receptors in allergic disease James Edward Pease, PhD, Timothy John Williams, PhD Journal of Allergy and Clinical Immunology Volume 118, Issue 2, Pages 305-318 (August 2006) DOI: 10.1016/j.jaci.2006.06.010 Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 The chemokine receptor repertoires of leukocytes implicated in the pathogenesis of allergic disease. As in Table I, those illustrated represent commonly agreed attributions. The near-ubiquitous expression of the homeostatic receptor CXCR4 is noteworthy. Journal of Allergy and Clinical Immunology 2006 118, 305-318DOI: (10.1016/j.jaci.2006.06.010) Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 2 An example of the links between the cytokine, chemokine, and cellular adhesion systems mediating the recruitment of effector cells at sites of allergic inflammation. Mo, monocyte; VCAM, vascular cell adhesion molecule. Journal of Allergy and Clinical Immunology 2006 118, 305-318DOI: (10.1016/j.jaci.2006.06.010) Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions