Robust embryo identification using first polar body single nucleotide polymorphism microarray-based DNA fingerprinting Nathan R. Treff, Ph.D., Jing Su,

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Presentation transcript:

Robust embryo identification using first polar body single nucleotide polymorphism microarray-based DNA fingerprinting Nathan R. Treff, Ph.D., Jing Su, M.Sc., Natasha Kasabwala, B.A., Xin Tao, M.Sc., Kathleen A. Miller, B.Sc., Richard T. Scott, M.D., H.C.L.D. Fertility and Sterility Volume 93, Issue 7, Pages 2453-2455 (May 2010) DOI: 10.1016/j.fertnstert.2009.08.070 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) The genotype similarity of each first polar body with each embryo biopsy within each patient's sample set. The designations of self (closed circle) or sibling (open square) are based on which oocyte the first polar body and embryo biopsy were derived from. (B) The genotype similarity of each first polar body with each buccal DNA sample within each patient's sample set. The designation of transferred sibling (open square) or transferred self (closed circle) is based on the embryo biopsy DNA fingerprinting result. Nontransferred sibling designation (open triangle) is based on knowledge of which embryos were not transferred and serves as a known sibling control to compare with predicted sibling case. Fertility and Sterility 2010 93, 2453-2455DOI: (10.1016/j.fertnstert.2009.08.070) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions