Genetic Blood Disorders

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Presentation transcript:

Genetic Blood Disorders Genetic Punnett Square Problems

How to solve Punnett Squares Video - link

Quick Genetics Review A gene consists of 2 alleles (represented by letters) Example: Genotype Phenotype PP widow’s peak Pp widow’s peak pp straight hairline

A person with a widow’ s peak (Pp) is married to a person with a straight hairline (pp), what percentage of their children will have straight hairline?

Two people who are both heterozygous for the widow’s peak trait are married. What percentage of their children will have straight hairline?

Genetics of Sickle Cell Anemia AA = normal Aa = sickle cell trait (Carrier) aa = sickle cell anemia

A female has sickle cell anemia and is married to a man who appears normal. A doctor tests the man and determines that he does NOT have sickle cell trait. What is the chance that this couple will have a child with sickle cell anemia?

The Genetics of Hemophilia Hemophilia is carried on the X chromosome. Females X H X H normal X H X h carrier X h X h hemophiliac Males X H Y normal X h Y hemophiliac

Video: What is a Pedigree? - link

Hemophilia What happens when a female who is a carrier marries a normal man?

What happens when a female who is normal marries a man who has hemophilia?