Loss of both chw-1 and sax-3 increases PDE axon pathfinding defects.

Slides:

Advertisements

Similar presentations

Studies of protein trap expression We compared the apparent intensity of GFP-protein staining in the GSCs with the RNA level of the corresponding gene.

Advertisements

Proteins enriched in HCs are strongly associated with genetic hearing/balance impairment. Proteins enriched in HCs are strongly associated with genetic.

History of previous tuberculosis (TB) treatment and prevalent TB in 24 high TB burden communities in Zambia and the Western Cape Province of South Africa,

Quantification of intracellular fuzzy staining (A) and of spherical bodies (B) in root cells upon an NaCl treatment. Quantification of intracellular fuzzy.

Role of C-terminal phosphorylation in the subcellular localization of AtPIP2;1.A, the figure shows typical laser-scanning confocal micrographs of the fluorescence.

Figure 5 Chp1 downregulation in zebrafish leads to CaP-MN, cerebellar, and movement defects rescued with WT, but not mutant CHP1 mRNA Chp1 downregulation.

Larval locomotion is impaired in HRS compared to control (HFP/w) in the presence of nematodes. Larval locomotion is impaired in HRS compared to control.

Lgc-35(L324S) homozygous knock-in animals exhibit less severe phenotypes than extrachromosomal or integrated transgene overexpression. lgc-35(L324S) homozygous.

nrde-3-dependent silencing of endogenous RNAi targets and transgenes.

Vagus Motor Neuron Topographic Map Determined by Parallel Mechanisms of hox5 Expression and Time of Axon Initiation Gabrielle R. Barsh, Adam J. Isabella,

Effects of drug concentration, driver, and genetic background on developmental abnormalities induced by GeneSwitch plus RU486. Effects of drug concentration,

CBS variant growth rates at various levels of exogenous cofactor supplementation. CBS variant growth rates at various levels of exogenous cofactor supplementation.

Basic SNP characteristics using different filter settings for missing data. Basic SNP characteristics using different filter settings for missing data.

Enriched gene functions responding to irradiance and pO2.

Expression of wc-1 driven by the vvd promoter in the Δvvd background is greater than in WT. DD is dark conditions, and LL is 25 μeinsteins·m2·s. Expression.

Seed set of 2xuief, 4xaly, and 4xaly 2xuief mutants in comparison to that of Col-0. Seed set of 2xuief, 4xaly, and 4xaly 2xuief mutants in comparison to.

In vivo BrdUrd incorporation kinetics of KTSL−/lo and KTSL− cells.

Phenotypic variation of sake yeast strains.

Mean score percentages and standard error bars of the diagnostic test immediately after the learning phase and one week later for integrated basic science.

Activation of the innate immune response may be radioprotective during larval development. Activation of the innate immune response may be radioprotective.

Effect of dinB gene deletion on the frequency of spontaneously arisen TetR mutants in different genetic backgrounds. Effect of dinB gene deletion on the.

Heat map of additive effects for PCs QTL

Immunohistochemical analysis of individual StanEx enhancer trap line expression in larval brain and VNC. Third larval instar CNS and VNC expression of.

Loss of FZR-1 results in elevated SAS-5 levels.

Characteristics of the Camphor-Off switch.

The volume per centre plotted against clinical outcomes which included Hospital Anxiety and Depression Scale (HADS) score, exercise 150 min, smoking, body.

Neuronal ATM level is reduced in mouse models of AD

T7 transcripts increase relative to E. coli transcripts over time.

Mean score percentages and standard error bars of the cued recall test immediately after the learning phase and one week later for integrated basic science.

Mean C-to-U editing ratios for most editing sites map to a region on chromosome 6 at 122 Mb. (A) Genome scan of mean C-to-U editing for 70 editing sites.

Islet Coordinately Regulates Motor Axon Guidance and Dendrite Targeting through the Frazzled/DCC Receptor Celine Santiago, Greg J. Bashaw Cell Reports

pkd1a/b and pkd2 interact in axial morphogenesis.

Sampling locations and IDs for accessions sequenced in this study.

Coalescent analysis of nucleotide differentiation between high and low latitude samples. Coalescent analysis of nucleotide differentiation between high.

Distribution of deletions and insertions in the ade6-(GACC)7ΔT repeat.

RT-PCR analysis of GFP splice variants in prp18a-1 mutants.

Modulation of life span by daf-12(null) mutation in animals with reduced DAF-2/InsR activity. Modulation of life span by daf-12(null) mutation in animals.

Loss of chw-1 but not crp-1 attenuates the defects in the VD/DD motor neurons driven by activated SAX-3. Loss of chw-1 but not crp-1 attenuates the defects.

Allele size distribution and frequency observed at 17 microsatellite loci in A. gambiae M (M, shaded bars), A. gambiae S (S, solid bars), and A. arabiensis.

MET activation increases the density of Syn-GFP/bassoon and Syn-GFP/PSD-95 clusters in neocortical neurons. MET activation increases the density of Syn-GFP/bassoon.

Frequency distribution of total leaf number for an F2 population derived from a cross of Van-0 with Ler, grown in long days. Frequency distribution of.

Spatial distribution of individual genotypes in a subpart (of size 500 grid units × 700 grid units) of the total grid after the last cycle in one replicate.

Manhattan plots for GWAS of LD50, µg/ml survival, 0

Loss of Cav1 function does not disrupt formation of dual projecting CPN/FPN axonal projections at P8. Loss of Cav1 function does not disrupt formation.

Apc2 localization and centrosome orientation are altered in Lar mutant GSCs. (A-B′) Apc2 (white, A,B; red, A′,B′) localization in wild-type (A,A′) and.

Comparison of rDNA histone modifications between mESCs and mNPCs.

Hepatic fuel metabolism in male 5αR1-KO and WT mice

SiRNA directed at Ngn1 inhibited differentiation of inner ear stem cells to β-III tubulin-positive cells. a, Inner ear stem cells treated with siRNA to.

Neighbor-joining tree of the 262 S

Least squares (LS) mean (SE) changes from baseline in (A) Cutaneous Lupus Erythematosus Disease Area and Severity Index activity scores and (B) Tender.

Percentage of culture-positive or PCR-positive sputum samples at stable state and exacerbation in year 1 and year 2 (full cohort, year 1 or year 2). a)

Diaphanous regulates the presynaptic actin cytoskeleton.

Effects of pain-stress on striatal dopamine release as a function of HTR2C genotype. Effects of pain-stress on striatal dopamine release as a function.

Complementation test of GN2.

Responses measured by BOLD fMRI in areas V1, V2, V3, and MT+ as two subjects (S2, gray; S3, black) switched between the speed and the contrast discrimination.

Trend of mean arterial blood pressure over time stratified by outcome defined by modified Rankin Scale (mRS) score: good outcome defined as mRS score ≤2;

Paraquat induces selective loss of subsets of dopaminergic neurons.

Effect of using β-actin as a denominator of IL-2 BAL fluid cell mRNA levels. Effect of using β-actin as a denominator of IL-2 BAL fluid cell mRNA levels.

Effects the genotypes of Rapgef2 and Rapgef6 on RG fiber organization and neuronal migration. Effects the genotypes of Rapgef2 and Rapgef6 on RG fiber.

Exogenous NR2B-expressing cells are more dynamic than control or exogenous NR2A-expressing cells. Exogenous NR2B-expressing cells are more dynamic than.

Case study showing significant epidural fat contraction after weight loss. Case study showing significant epidural fat contraction after weight loss. The.

SLC30A10 protects DAergic neurons from neurodegeneration induced by Mn exposure. SLC30A10 protects DAergic neurons from neurodegeneration induced by Mn.

Simvastatin does not correct AGS in the Fmr1-/y mouse.

CA1 neuronal loss and recovery following forebrain ischemia.

KRASG12D- and BRAFV600E-induced survival in PDECs requires IGF1R signaling. KRASG12D- and BRAFV600E-induced survival in PDECs requires IGF1R signaling.

NYHA before and after at least 30–60 days after TAVI

ENTPD5 expression correlates with EGFR and activated AKT levels in human NSCLC. A, percentages of PTEN-low lung adenocarcinoma cases with at least one.

Percentage of pneumococcal isolates within each vaccine group for 2001 and Percentage of pneumococcal isolates within each vaccine group for 2001.

Fgfr1a, fgfr1b, and fgfr2 function redundantly to regulate pectoral fin development. fgfr1a, fgfr1b, and fgfr2 function redundantly to regulate pectoral.

Volume 18, Issue 6, Pages (June 2010)

Presentation transcript:

Loss of both chw-1 and sax-3 increases PDE axon pathfinding defects. Loss of both chw-1 and sax-3 increases PDE axon pathfinding defects. Quantitation of PDE defects. lqIs2 is the osm-6::gfp control transgene. The Y-axis denotes the genotype and the X-axis represents the percentage of ectopic lamellipodia formation. At least 100 neurons were scored for each genotype. *P < 0.0001 as determined by Fisher Exact Analysis. The error bars represent the standard proportion of the mean. Jamie K. Alan et al. G3 2018;8:1885-1895 ©2018 by Genetics Society of America