Heparin-associated thrombocytopenia and thrombosis: A serious clinical problem and potential solution Raymond G. Makhoul, M.D., Charles S. Greenberg,

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Presentation transcript:

Heparin-associated thrombocytopenia and thrombosis: A serious clinical problem and potential solution Raymond G. Makhoul, M.D., Charles S. Greenberg, M.D., Richard L. McCann, M.D. Journal of Vascular Surgery Volume 4, Issue 5, Pages 522-528 (November 1986) DOI: 10.1016/0741-5214(86)90390-3 Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 1 Effect of aspirin in vivo on platelet aggregation. Addition of 1 U/ml of beef lung heparin to platelet-rich plasma of patient before and after aspirin ingestion. Journal of Vascular Surgery 1986 4, 522-528DOI: (10.1016/0741-5214(86)90390-3) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 2 Effect of adding beef lung heparin (1 U/ml) and Org 10172 (0.20 mg/ml) to normal platelets (0.30 ml) and platelet-poor plasma (0.15 ml) of patient. Journal of Vascular Surgery 1986 4, 522-528DOI: (10.1016/0741-5214(86)90390-3) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions